Dymista Allergen Chamber - Onset of Action Study

Clinical Trial Summary

This study is to assess the onset of action of fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray (Dymista) in treating the nasal symptoms of seasonal allergic rhinitis (SAR) induced by an allergen challenge in an Environmental Exposure Unit (EEU).

See also
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Completed	`NCT00209365` - The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit	N/A
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Recruiting	`NCT05346718` - Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic Rhinitis	N/A
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Completed	`NCT02245360` - Study Immunology and Safety of 60-day Treatment of SQ Grass SLIT (Sublingual Immunotherapy)-Tablet in Adult Subjects With Grass Pollen-induced Allergic Rhinoconjunctivitis	Phase 3
Completed	`NCT01940146` - Efficacy and Safety of SPARC1310 in Seasonal Allergic Rhinitis	Phase 2
Completed	`NCT01230619` - Vienna Challenge Chamber Study Using RV658 in Subjects With Allergic Rhinitis	Phase 2
Completed	`NCT00574210` - PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)	Phase 2
Completed	`NCT00561717` - A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis	Phase 4
Completed	`NCT00420082` - A Randomized, Double-Blind, 4-way Crossover Study to Evaluate the Efficacy of Bilastine in the Vienna Challenge Chamber	Phase 2
Completed	`NCT00405899` - Pilot Study of Allergy Immunotherapy and Prevention of Viral Respiratory Infections	N/A
Completed	`NCT00443495` - Phase I/IIa Study on Chitin Microparticles in Subjects Suffering From Allergic Rhinitis	Phase 1/Phase 2
Completed	`NCT03097432` - Non-interventional Study to Assess the Tolerability, the Safety Profile and the Adherence of Different Up-dosing Schemes for a Sublingual Immunotherapy Treatment	N/A

NCT number	NCT04652245
Study type	Interventional
Source	Viatris Inc.
Contact
Status	Completed
Phase	Phase 4
Start date	December 14, 2020
Completion date	December 13, 2021

Dymista Allergen Chamber - Onset of Action Study

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms