CryoBalloon Focal Ablation System for Residual Barretts Esophagus Post Ablation; a Pilot Study.
This study is being done to see if treating residual Barrett's Esophagus after previously having undergone Radiofrequency ablation or Endoscopic Mucosal resection can be eliminated with focal cryotherapy.
NCT02230410 — Barrett's Esophagus
Status: Completed
http://inclinicaltrials.com/barrett-s-esophagus/NCT02230410/
Notch Signaling and Novel Biomarkers for Barretts Esophagus
This research study hopes to identify new molecular markers in the tissue of Barrett's esophagus that will help physicians better understand and manage this condition. Patients undergoing an upper endoscopy will be asked to complete a gastroesophageal reflux disease (GERD) questionnaire, provide a blood sample and allow additional biopsies to be taken during the procedure.
NCT01484925 — Barrett's Esophagus
Status: Completed
http://inclinicaltrials.com/barrett-s-esophagus/NCT01484925/
Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts Esophagus
The hypothesis of this study was that the comparative effectiveness of unsedated transnasal endoscopy (uTNE) will be greater than sedated endoscopy (sEGD) in population screening for BE.
NCT01288612 — Barrett's Esophagus
Status: Completed
http://inclinicaltrials.com/barrett-s-esophagus/NCT01288612/
Confocal Laserscanning Microscopy for Detection of Barretts Esophagus. A Blinded Multi-Center Study.
Four quadrant biopsies in regular ranges is the goldstandard in monitoring this disease. The ideal situation for the endoscopist is to visualize cellular structures, which implies having microscopic imaging available. A potential candidate to fill this gap could be confocal fluorescence microscopy (Cellvizio®-GI and Mauna Kea Technologies). To compare the gold standard with the confocal fluorescence microscopy for detection of metaplastic - or intraepithelial neoplastic changes of barrett-suspicious esophageal mucosa this study has been initiated.
NCT00449995 — Barrett Esophagus
Status: Completed
http://inclinicaltrials.com/barrett-esophagus/NCT00449995/
Endoscopic Therapy of Early Cancer in Barretts Esophagus
This study is being done to see if treatment for esophageal cancer can be done using endoscopy for patients ineligible for surgical or radiological therapy. The standard method of treating this type of cancer is surgical removal of the esophagus. The study will determine if removing just the cancer with endoscopy is enough treatment or if the addition of another treatment called photodynamic therapy (treatment with a red light and a drug called sodium porfimer) is needed.
NCT00217087 — Barrett Esophagus
Status: Completed
http://inclinicaltrials.com/barrett-esophagus/NCT00217087/