Sars-CoV2 Clinical Trial
— CRASHOfficial title:
COVID-19 Respiratory Distress and Antithrombotic Drugs inSubject's Habits
| NCT number | NCT04412473 |
| Other study ID # | 7837 |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | April 30, 2020 |
| Est. completion date | June 2021 |
Current management of VID-19 consists of oxygen support without specific treatment. Hospitalization may suddenly require delayed resuscitation. This evolution corresponds to an atypical acute respiratory distress syndrome (ARDS), the mechanism of which is poorly understood and difficult to predict. The general pathophysiology of ARDS, the vascular tropism of SARS-Cov2, the description of coagulopathy and numerous pulmonary artery thromboses in resuscitation and the encouraging investigation of antithrombotics in general ARDS
| Status | Recruiting |
| Enrollment | 1000 |
| Est. completion date | June 2021 |
| Est. primary completion date | June 2021 |
| Accepts healthy volunteers | |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Major Subject (=18 years) - Subject hospitalised in HUS or GHRMSA for COVID-19 - The diagnosis COVID-19 confirmed by smear or evoked by CT scan or chest X-ray without a differential diagnosis retained in the medical record - Subjects who, after being informed, do not wish to have their data reused for the purposes of this research Exclusion Criteria: - Subject who expressed opposition to participating in the study - Subject under guardianship or trusteeship - Subject under safeguard of justice - Patient hospitalized in a geriatric service or in a ward not labeled COVID (surgery, oncology,...) or in a short-term hospitalization unit without transfer to another service. - Serious patient on admission to the emergency room and recused from resuscitation. |
| Country | Name | City | State |
|---|---|---|---|
| France | Service Médecine Intensive et Réanimation | Strasbourg |
| Lead Sponsor | Collaborator |
|---|---|
| University Hospital, Strasbourg, France |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Analysis of Respiratory Distress and Antithrombolytic Therapy in Patients with covid19 | 1 month |
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