Burn Injuries During COVID-19 Pandemic and Its Influence on Length of Stay

SARS-CoV-2 Infection Clinical Trial

Official title:

Anesthetic Experience and Patients 'Prognosis of SARS-CoV-2 Positive Versus Negative Burns Patients: An Observational Case -Control Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06330389
• Other study ID #: MRC-01-20-1074
• Status: Completed
• Start date: April 1, 2020
• Est. completion date: June 25, 2021

Study information

• Verified date: June 2021
• Source: Hamad Medical Corporation
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Burn injuries were thought to be difficult to treat during the new corona virus epidemic. Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.

Description:

1. Introduction / History

The world is being attacked by the rapidly expanding severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) epidemic, which is exacerbating an economic crisis. SARS-Cov-2 is the cause of the coronavirus disease 2019 (COVID-19). Anaesthetists are at risk for contracting a virus while doing their regular duties because they frequently come into touch with respiratory droplets.

All nations have put protective and preventive measures in place, forcing people to spend more time at home. A Brazilian study discovered that during the COVID-19 pandemic period, spending more time at home increased exposure to sanitizing products, which include ethanol and hydrogen peroxides that can cause burn injuries.

Aim of our Study:

Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.

Inclusion Criteria:

Patients who had the burn graft surgery at Al Wakrah Hospital; Hamad Medical Corporation between from 1st of April to end of November 2020. Planned number will include all COVID-19 positive and negative subjects in this period.

Data Source The electronic medical record (Cerner) used in order to identify patients who match study defined criteria. The investigators can Collect data directly from Cerner to excel sheet

Variable Abstraction Patient demographic and clinical data will be collected including age, morbidities, presenting symptoms, physical examination, laboratory investigations, intraoperative data, type of surgery, postoperative course, survival, and length of hospital stay and follow up.

In addition, the type of anesthesia is also included as factor for further complications ex general anesthesia, spinal or combined spinal epidural type.

Observation full reviewing of their medical illness and chart laboratory and investigations will be collected after getting approval of MRC and IRB committee.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 70
• Est. completion date: June 25, 2021
• Est. primary completion date: March 1, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• All burn injuries required surgery with COVID-19 positive or negative status

Exclusion Criteria:

• Other surgery during COVID-19 pandemic

Related Conditions & MeSH terms

• COVID-19
• SARS-CoV-2 Infection

Intervention

Procedure:
• Burn Injuries Graft Surgery
Burn Injuries Graft Surgery

Locations

Country	Name	City	State
Qatar	HAMAD Medical Corporation- Al Wakra Hospital	Doha

Sponsors (1)

Lead Sponsor	Collaborator
Hamad Medical Corporation

Country where clinical trial is conducted

Qatar, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.	Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.	60-90 days
Secondary	Clinical diffreneces between burn injuries with positive vs negative COVID-19 status	Details for those risk Factors: BMI; Pre Op Lab data, Intra Op data ex. blood loss / ml, transfusions/ ml or Unit , surgery time/ min, etc, Post operative data and ICU admission data, , lab parameters, INR,LFTs/unit , required blood transfusions/ml or Unit , re intubation times, vasopressor needs. Analyze lab values /unit, check number of days in hospital stay and ICU stay .; Analyze risk factors which affect hospital length of stay. Analyze risk factors using cox regression and investigate hazard ratio for each one to determine which is independent risk factor OR associated factor.	60-90 days