Sarcopenia Clinical Trial
Official title:
The Effects of Whey Protein and Collagen on Fat Free Mass, Muscle Strength and Wound Healing in Elderly Patients Undergoing Elective Knee- or Hip Surgery
Verified date | September 2021 |
Source | University of Copenhagen |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of the study is to compare the effect of whey protein and collagen on fat free mass, muscle strength, functional ability, wound healing and life quality in elderly patients undergoing elective knee- or hip surgery (defined as elective knee- or hip arthroplasty). The patients are admitted at the department of Orthopaedic Surgery at Herlev Gentofte Hospital.
Status | Completed |
Enrollment | 15 |
Est. completion date | December 30, 2020 |
Est. primary completion date | November 30, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years and older |
Eligibility | Inclusion Criteria: - Age 65+ years - Scheduled elective knee- or hip surgery - Must be able to understand and speak danish - Must be able to chew and swallow food with a regular consistency - Must be able to consume the assigned protein supplementation - Must be able to consent participation Exclusion Criteria: - Vegan - Demensia - Critical complications to the surgery which prevents the patient from participating in the rehabilitation program - Plasma-creatinin above 250 micromol/L - Palliative patients - Known intolerance of whey protein and/or collagen - Patients with a pacemaker |
Country | Name | City | State |
---|---|---|---|
Denmark | Herlev/Gentofte Hospital | Gentofte | Hellerup |
Lead Sponsor | Collaborator |
---|---|
University of Copenhagen | Herlev and Gentofte Hospital |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Palatability of the protein supplementation | Assessed on a scale from 1-5 | 30 days | |
Other | Consistency of the protein supplementation | Assessed on a scale from 1-5 | 30 days | |
Other | Compliance of the protein supplementation intake | Assessed trough a weekly form, which the participants will fill in | Weekly for 30 days | |
Other | Rapported side effects | Participants will be informed to rapport if they experience any side effects throughout the intervention | 30 days | |
Primary | The difference in fat free mass | The outcome will be monitored through BIA and the development of fat free mass in the operated leg will be compared to the development of fat free mass in the non-operated leg. | Weekly for 30 days | |
Secondary | Wound healing | The amount of days until the wound is healed (defined as: the epithelium is covered without crust). This will be monitored trough pictures and assessed on a scale from 1-5 by a masked doctor. | Weekly for 30 days | |
Secondary | Redness and infection | The redness and infection around the wound assessed on a scale from 1-5 by a masked doctor through pictures. | Weekly for 30 days | |
Secondary | Handgrip strength | Handgrip strength measured by a handdynanometer (SAEHAN) in kg and percentage | Weekly for 30 days | |
Secondary | Extension strength of quadriceps femoris | Measured in amounts of repetitions of 0.5 or 1.0 kg. | Weekly for 30 days | |
Secondary | Life quality | Measured trough EuroQol-5D-5L | Weekly for 30 days | |
Secondary | Difference in functional ability (NMS) | Assessed by New mobility score | Weekly 30 days | |
Secondary | Difference in Chair stand test | Measured by amount of repetitions | Weekly for 30 days |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT06287502 -
Efficacy of Structured Exercise-Nutritional Intervention on Sarcopenia in Patients With Osteoporosis
|
N/A | |
Recruiting |
NCT05063279 -
RELIEF - Resistance Training for Life
|
N/A | |
Completed |
NCT03644030 -
Phase Angle, Lean Body Mass Index and Tissue Edema and Immediate Outcome of Cardiac Surgery Patients
|
||
Recruiting |
NCT06143592 -
Inspiratory Muscle Training on Balance, Falls and Diaphragm Thickness in the Elderly
|
N/A | |
Terminated |
NCT04350762 -
Nutritional Supplementation in the Elderly With Weight Loss
|
N/A | |
Enrolling by invitation |
NCT05953116 -
Managing the Nutritional Needs of Older Filipino With Due Attention to Protein Nutrition and Functional Health Study
|
N/A | |
Recruiting |
NCT04028206 -
Resistance Exercise or Vibration With HMB for Sarcopenia
|
N/A | |
Enrolling by invitation |
NCT03297632 -
Improving Muscle Strength, Mass and Physical Function in Older Adults
|
N/A | |
Completed |
NCT04015479 -
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults
|
N/A | |
Completed |
NCT03234920 -
Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver Transplantation
|
N/A | |
Recruiting |
NCT03998202 -
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
|
||
Recruiting |
NCT04717869 -
Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
|
||
Completed |
NCT05497687 -
Strength-building Lifestyle-integrated Intervention
|
N/A | |
Completed |
NCT03119610 -
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
|
Phase 1/Phase 2 | |
Recruiting |
NCT05711095 -
The Anabolic Properties of Fortified Plant-based Protein in Older People
|
N/A | |
Recruiting |
NCT05008770 -
Trial in Elderly With Musculoskeletal Problems Due to Underlying Sarcopenia - Faeces to Unravel Gut and Inflammation Translationally
|
||
Not yet recruiting |
NCT05860556 -
Sustainable Eating Pattern to Limit Malnutrition in Older Adults
|
||
Recruiting |
NCT04522609 -
Electrostimulation of Skeletal Muscles in Patients Listed for a Heart Transplant
|
N/A | |
Recruiting |
NCT04545268 -
Prehabilitation for Cardiac Surgery in Patients With Reduced Exercise Tolerance
|
N/A | |
Recruiting |
NCT03160326 -
The QUALITY Vets Project: Muscle Quality and Kidney Disease
|