Exercise Intervention for Patients With Sarcopenia or Frailty in Long-term Care Institutions

Sarcopenia Clinical Trial

Official title:

Exercise Intervention for Patients With Sarcopenia or Frailty in Long-term Care Institutions

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03650907
• Other study ID #: SarcExercise
• Status: Completed
• Phase: N/A
• Start date: August 24, 2018
• Est. completion date: May 31, 2019

Study information

• Verified date: August 2019
• Source: Chang Gung Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Sarcopenia is a geriatric syndrome of decreased muscle volume with muscular function decline. There is more tendency for sarcopenic elderly to be frail, disabled, or have cardiovascular disease. Compared to those who are not sarcopenic, they also had worse prognosis in response to treatment for definite diseases, and spend more medical cost.

Exercise appears to have an important role in management of sarcopenia. In the current study, the investigators provide an exercise program, including resistance/balance training for the elderly with sarcopenia or frailty in long-term care institution, and evaluate the effect.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: May 31, 2019
• Est. primary completion date: May 31, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 110 Years

Eligibility

Inclusion Criteria:

1. >20-year-old

2. diagnosed with sarcopenia (by the definition from Asia workgroup for sarcopenia, AWGS) or frailty (The Fried model, based on five functional criteria)

Exclusion Criteria:

1. Severe medical diseases or mental problems, which result in difficulty to follow exercise program.

2. Inability to get down from bed for activity due to disease, such as neuropathy or orthopedic disease.

3. High risk group for exercise program, such as those with unstable fracture or nonunion fracture.

4. Anyone who didn't want attend this study.

Related Conditions & MeSH terms

• Frailty
• Sarcopenia

Intervention

Behavioral:
• Group exercise program
Patients in experimental group attend group exercise program, instructed by fitness trainer, at long-term care institutions. Frequency: 3 times per week. Type: resistance/flexibility/balance training, including warm-up and cold-down. Duration: 1 hour per time, for 16 weeks.
• Self exercise program
Patients in control group receive oral education for self exercise program, mainly resistance muscle training. Patients are requested to do self-training for 16 weeks.

Locations

Country	Name	City	State
Taiwan	Bor-Ay Sweet home	Keelung

Sponsors (1)

Lead Sponsor	Collaborator
Chang Gung Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle strength	grasp strength by dynamometer	after 16-weeks training
Primary	walk speed	6-meter walk test	after 16-weeks training