Early Detection of Disability and Health Promotion for Community-dwelling Elderly

Sarcopenia Clinical Trial

Official title:

Department of Physical Therapy, Tzu Chi University

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03607136
• Other study ID #: IRB106-75-A-2
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 2018
• Est. completion date: July 2020

Study information

• Verified date: July 2018
• Source: Buddhist Tzu Chi General Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluates the effects of exercise intervention on muscle strength and walking speed for the community-dwelling elderly. Half of the participants will receive exercise training, while the other half will maintain their usual activities of daily living.

Description:

Physical inactivity can result in physical frailty and sarcopenia. Physical frailty and sarcopenia are two common and mostly overlapping geriatric conditions, which may cause negative consequences of aging, such as disability, hospitalization and mortality.

Regular physical activity has been suggested to maintain or improve functional capacity and body composition, as well as delay aging process. Nevertheless, inactivity prevalence still significantly increases among older adults, especially those with a disability. One of the probable reasons is that the use of physical activities or exercise interventions is not tailored to the needs and capabilities of the elderly.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 60
• Est. completion date: July 2020
• Est. primary completion date: July 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 50 Years to 80 Years

Eligibility

Inclusion Criteria:

• age greater than 50 years

• able to follow simple instructions

• willing to participate and sign consent form

Exclusion Criteria:

• unstable angina or epilepsy

• severe visual deficits

• cognitive dysfunction

• other musculoskeletal conditions that will limit mobility

Related Conditions & MeSH terms

• Elderly
• Sarcopenia

Intervention

Other:
• exercise training
Aerobic exercises, strengthening exercises, flexibility training for 60min, twice a week for 12 weeks

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Buddhist Tzu Chi General Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Walking speed	Participants are asked to walk along a 14 m hallway. The time taken to the middle 10 m is recorded to calculate walking speed (m/s).	Change from baseline at 12 weeks
Primary	Muscle strength	Muscle strength is assessed using hand-hold Dynamometers	Change from baseline at 12 weeks
Secondary	Timed up and go test	Participants are asked to stand up, walk 3 m, turn around a cone, and return to a sitting position	Change from baseline at 12 weeks
Secondary	Walking endurance	Participants are asked to walk back and forth along a 20-meter corridor and to cover the maximum distance possible in six minutes	Change from baseline at 12 weeks
Secondary	Sit-to-stand test	Participants are asked to stand up and sit down 5 times.	Change from baseline at 12 weeks
Secondary	Berg balance scale	It consists of 14 items, including sitting unsupported, standing unsupported, standing with eyes closed, standing with feet together, standing on one foot, turning to look behind, retrieving objective from floor, random standing, reaching forward with an outsrptretched arm, sit to stand, stand to sit, transfer, turning 360 degrees, stool stepping, scored from 0 to 4, "0" indicates the lowest level of function and "4" the highest level of function. Total Score = 56.	Change from baseline at 12 weeks
Secondary	Gait kinematics	Gait kinematics are assessed by angular displacement of lower limbs using shoe-worn inertial measurement unit based device	Change from baseline at 12 weeks