Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women

Sarcopenia Clinical Trial

Official title:

Protein Intake Immediately After Resistance Exercise Does Not Promote Additional Increase on Lean Mass, Strength and Functional Capacity in Postmenopausal Women: a Randomized Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03372876
• Other study ID #: 2.023.127
• Status: Completed
• Phase: N/A
• First received: December 10, 2017
• Last updated: December 13, 2017
• Start date: May 8, 2017
• Est. completion date: October 11, 2017

Study information

• Verified date: December 2017
• Source: Federal University of Uberlandia
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluated the effect of protein intake immediately after resistance exercise on lean mass, strength, and functional capacity gains in postmenopausal women. Participants were randomly assigned to protein-carbohydrate group (PC) (n=17), that ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon; and to carbohydrate-protein group (CP) (n=17), that ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. Both groups performed the same resistance training protocol in the morning.

Description:

Both groups performed the same training protocol, differing only the time of protein or carbohydrate supplementation. The dietary assessment was made through the 24-hour food recall, being conducted at the beginning, middle and end of the intervention. Resistance exercises for upper and lower limbs will be performed, at 70% of one repetition maximum. One maximum repetition (1-RM), handgrip strength and 1-mile walk were performed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: October 11, 2017
• Est. primary completion date: October 4, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Women in the postmenopausal period (menopausal for at least one year, confirmed by laboratory diagnostic tests menopause - LH and high FSH and estradiol decreased);

• Healthy;

• Who agree to participate and sign the consent term.

Exclusion Criteria:

• The one who does not provide the necessary information for the development of the study;

• Present orthopedic limitations;

• Patients with previously diagnosed and treatment of diseases such as type II diabetes mellitus, hypertension and cardiovascular disease.

Related Conditions & MeSH terms

• Sarcopenia

Intervention

Dietary Supplement:
• Protein and carbohydrate supplementation
Participants were randomly assigned to protein-carbohydrate group (PC) (n=17), that ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon; and to carbohydrate-protein group (CP) (n=17), that ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. Both groups performed the same resistance training protocol in the morning, 3 times a week, at 70% of 1-maximum repetition (1-RM) during 8 weeks.

Locations

Country	Name	City	State
Brazil	Erick P. de Oliveira	Uberlândia	Minas Gerais

Sponsors (1)

Lead Sponsor	Collaborator
Federal University of Uberlandia

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in the lean mass of postmenopausal women practicing resistance exercise		Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)
Secondary	Changes on strength of postmenopausal women practicing resistance exercise		Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)
Secondary	Changes on functional capacity of postmenopausal women practicing resistance exercise		Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)