The Benefits of Hemp Protein Supplementation During Resistance Training

Sarcopenia Clinical Trial

Official title:

The Benefits of Hemp Protein Supplementation During Resistance Training

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02529917
• Other study ID #: 15-95
• Status: Completed
• Phase: N/A
• First received: August 11, 2015
• Last updated: May 2, 2017
• Start date: August 2015
• Est. completion date: December 2015

Study information

• Verified date: May 2017
• Source: University of Saskatchewan
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Forty physically active men and women aged 18-45y will take part in an 8-week resistance training program, randomized (double blind) 1:1 into each of two groups. Twenty participants will be randomized to receive 60 g/d of hemp powder (containing approximately 40 g protein and 9 g oil) supplementation and 20 randomized to receive 60 g/d of soy supplementation (matched to the hemp for macronutrients and calories) during eight weeks of training. Each participant will complete testing before and after the intervention for assessment of body composition (lean tissue, fat, and bone mass), strength, central fatigue, markers of inflammation, and bone resorption. Over the 8-weeks of training, participants will train four-five days per week for 1-1.5 hours per session with exercises targeting all major muscle groups. The training will involve a "two day split" where different muscle groups are trained on two consecutive days (day 1 involves chest, back, and arms; day 2 legs, shoulders, and abdominals). Resistance training will provide the necessary stimulus for protein synthesis to optimize the effect of a protein-containing nutritional supplement. The hemp or soy powder will be consumed in two doses (i.e. 30 g powder containing 20 g protein per dose) immediately after exercise sessions and one hour after exercise. This dosing regimen is optimal for stimulating muscle protein synthesis and building muscle mass . On the one non-training day per week the two doses will be consumed with meals.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: December 2015
• Est. primary completion date: December 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• At least 6 months experience with resistance training

Exclusion Criteria:

• Allergies to hemp or soy

• Consumption of other nutritional supplements in previous month

• Answered "yes" to questions on the Physical Activity Readiness Questionnaire

Related Conditions & MeSH terms

• Sarcopenia

Intervention

Dietary Supplement:
• Hemp powder
Hemp powder supplement
• Soy Powder
Soy powder supplement

Locations

Country	Name	City	State
Canada	University of Saskatchewan	Saskatoon	Saskatchewan

Sponsors (1)

Lead Sponsor	Collaborator
University of Saskatchewan

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in lean tissue mass (kg)	Lean tissue mass measured with dual energy x-ray absrorptiometry	8 weeks
Secondary	Change in fat mass (kg)	Fat mass as measured by dual energy x-ray absorptiometry	8 weeks
Secondary	Change in bone mass (grams)	Bone mass as measured by dual energy x-ray absorptiometry	8 weeks
Secondary	Change in elbow flexor muscle thickness (cm)	Muscle thickness as assessed by ultrasound	8 weeks
Secondary	Change in knee extensor muscle thickness (cm)	muscle thickness as measured by ultrasound	8 weeks
Secondary	Change in bench press strength (kg)	Bench press strength as assess on a plate-loaded machine by the 1-RM method	8 weeks
Secondary	Change in arm curl strength (kg)	Arm curl strength as assessed with dumbbells by the 1-RM method	8 weeks
Secondary	Change in leg press strength (kg)	Leg press strength as assessed on a leg-press machine by the 1-RM method	8 weeks
Secondary	Change in inflammation by interleukin-6 (mmol/l) levels	Interleukin-6 levels measured from saliva samples	8 weeks
Secondary	Change in inflammation by C-reactive protein (mmol/l) levels	C-reactive protein levels measured from saliva samples	8 weeks
Secondary	Change in bone resorption (N-telopeptides) (mmol/l)	N-telopeptides measured from urine samples	8 weeks
Secondary	Change in voluntary muscle activation (Nm)	Voluntary muscle activation as measured by the interpolated twitch technique	8 weeks