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TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients

Sarcoma, Soft Tissue Clinical Trial

Official title:
A Perspective Phase I and II Trial of Liposome-encapsulated Doxorubicin (TLC D-99) in Combination With Ifosfamide in Patients With Metastatic Soft Tissue Sarcoma

Clinical Trial Summary

The purpose of this study is to determine the maximum tolerated dose of the TLC D-99 combined with ifosfamide and then the efficacy of this combination in terms of overall response rate, time to progression and time of response

Clinical Trial Description

The Maximum Tolerated Dose of the combination was determined and the Phase I terminated.

Then, Phase II study started. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00289809
Study type Interventional
Source Istituto Clinico Humanitas
Contact
Status Completed
Phase Phase 1/Phase 2
Start date September 2006
Completion date December 2009
View Details
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