Sarcoma, Soft Tissue Clinical Trial
Official title:
A Phase II Study Evaluating Efficacy of the Combination of Gemcitabine and Vinorelbine in Advanced Soft Tissue Sarcoma
The purpose of this study is to determine if the combination of gemcitabine and vinorelbine is effective in treating patients with advanced soft tissue sarcoma.
Patients will receive both gemcitabine and vinorelbine once a week for two weeks and then
one week with no chemotherapy (1 cycle equals 21 days). Gemcitabine and vinorelbine will be
administered on day 1 and day 8 of each cycle.
Blood tests will be performed on each day chemotherapy is administered. A CT scan will be
done after every 2 cycles (approximately every 6 weeks) to determine the effects of the
chemotherapy on the sarcoma.
A physical exam will be performed at the start of chemotherapy and at least every three
weeks thereafter.
Patients will remain on this study as long as the disease does not progress or there are no
unacceptable side effects.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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