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Trial of Antimycobacterial Therapy in Sarcoidosis — CLEAR  

Sarcoidosis Clinical Trial

Official title:
Phase I/II Study of the Effects of Antibiotics on Sarcoidosis Pathogenesis

Clinical Trial Summary

Growing research from independent laboratories provide an association between mycobacteria and sarcoidosis. More recent immunologic and molecular studies demonstrate immune responses to mycobacteria virulence factors. We hypothesize that sarcoidosis pathogenesis reflects an immune response against metabolically-active mycobacterial species. The purpose of this study is to assess if administration of anti-mycobacterial drug therapy will aid in resolution of cutaneous sarcoidosis lesions.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01074554
Study type Interventional
Source Vanderbilt University
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date February 2010
Completion date February 2011
View Details
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