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Safety clinical trials

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NCT ID: NCT03308929 Active, not recruiting - Safety Clinical Trials

Prospective G7 Dual Mobility Total Hip PMCF

Start date: February 28, 2017
Phase:
Study type: Observational

This is a prospective multi-center clinical evaluation following recipients of the G7 Dual Mobility hip device. The primary objective is to characterize survivorship of the G7 hip at five years post-index procedure. Secondary objectives include documentation of clinical outcomes, safety and radiographic data.

NCT ID: NCT03300466 Completed - Safety Clinical Trials

A Study to Evaluate the Performance and Safety of GP0045 for Correction of Moderate to Severe Nasolabial Folds

Start date: October 2, 2017
Phase: N/A
Study type: Interventional

This is a study to assess the performance and safety of GP0045 when injected in the nasolabial folds. There is an 18 months follow up period.

NCT ID: NCT03223142 Recruiting - Neoplasm Metastasis Clinical Trials

Standardization of Multi-modal Tumor Ablation Therapy System

SMTATS
Start date: July 2017
Phase: N/A
Study type: Interventional

This study will document for the safety and efficacy of image guided multi-mode precision ablation system (the combination of cryoablation and radiofrequency ablation) for the treatment of liver malignant, as well as provide the indicator of antitumor immune response for liver malignant in China.

NCT ID: NCT03140098 Withdrawn - Safety Clinical Trials

Evaluation of COVA™+ CARD in Adult Cardiac Surgery

Start date: February 2017
Phase:
Study type: Observational

The aim of this observational study is to evaluate the safety of the guided healing and adhesion prevention membrane, COVA™+ CARD, in adult cardiac surgery. The causality of the collagen membrane according to the occurrence of peri and post-operative complications will be evaluated.

NCT ID: NCT03133325 Completed - Safety Clinical Trials

A Study to Evaluate the Safety Following Injection of GP0045 Compared to Restylane Lyft Lidocaine

Start date: April 19, 2017
Phase: N/A
Study type: Interventional

This is a study to assess the safety of GP0045 compared to Restylane Lyft Lidocaine. There is a 12-week follow-up period. AEs will be recorded throughout the study.

NCT ID: NCT03120091 Completed - Safety Clinical Trials

Assessment of the Accuracy,Feasibility,Safety of Continuous Glucose Monitoring System

Start date: July 1, 2014
Phase: N/A
Study type: Observational

Real-time continuous glucose monitoring system (CGMS) has been attempted to be used in ICU, but its feasibility, accuracy and confounding factors are controversial.

NCT ID: NCT03067363 Terminated - Safety Clinical Trials

First in Human Single Ascending Dose Study of MOR107

Start date: February 16, 2017
Phase: Phase 1
Study type: Interventional

This is the first in human study of MOR107. It is a 2 part, single centre, double-blind, randomised, placebo-controlled study in healthy male subjects. Part 1 is a single ascending dose study, and Part 2 is a parallel group, dose range finding study in healthy male subjects on a low sodium diet.

NCT ID: NCT03033342 Completed - Safety Clinical Trials

Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4

Start date: August 2, 2016
Phase: Phase 1
Study type: Interventional

A phase one study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. Cohorts of healthy adults (female and male) will participate in: single dose escalation study of increasing doses of MRX-4 given by mouth others will participate in multiple dose escalation cohorts of MRX-4 given twice daily by mouth. other cohorts of subjects will participate in the study to evaluate the impact of concomitant food or Omeprazole on safety, tolerability and pharmacokinetics of MRX-4

NCT ID: NCT03033329 Completed - Safety Clinical Trials

Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4

Start date: October 2016
Phase: Phase 1
Study type: Interventional

A Phase 1 study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. In Part 1 cohorts of healthy adults will participate in a single dose escalation study of increasing intravenous doses of MRX-4. In Part 2 cohorts of healthy adults will participate in a multiple dose escalation study of increasing intravenous doses of MRX-4 given twice daily for ten days. Part 3 is a crossover study of oral MRX-4 versus a comparable intravenous dose of MRX-4 to determine bioavailability.

NCT ID: NCT02693587 Recruiting - Safety Clinical Trials

Misodel or Angusta for Induction of Labour?

Start date: November 2015
Phase: N/A
Study type: Observational [Patient Registry]

In Denmark, every 4 birth induced, most often due to prolonged pregnancy, up til 10-12 days after term. A group (RADS) set up by the Danish Regions has recently recommended induction with prostaglandins in tablet form (Angusta®). The recommendation is based primarily on the results of a meta-analysis published by the Cochrane Library, where various prostaglandin medications were compared. Vaginal prostaglandin insert (Misodel®) have proved safe in American Studies and is registered in Denmark for use of induction. Misodel® was not included in RADS's evaluation, as there are only few studies on the effectiveness and side effects. In the current study, investigators want to compare two different regimes for the induction of primipara who use respectively Misodel® and Angusta® as the primary method. The study is based on prospective collection of data from three divisions in Region Zealand, where investigators primarily compare the efficacy and safety but also to evaluate women's experience, the cost of medicine and consumption of resources in the maternity wards.