Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

Safety Issues Clinical Trial

Official title:

Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode With Maquet Flow-i Anaesthesia Machine

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03465475
• Other study ID #: Inonu uni
• Status: Completed
• Start date: July 1, 2018
• Est. completion date: March 1, 2021

Study information

• Verified date: August 2021
• Source: Inonu University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

Description:

After the ethical approvel 60 adult patients scheduled for hepatectomy will be taken to study. Patients will be monitored after they are taken to the operating room (ECG, NIBP, SpO2, Body Temp, BIS, NIRS, PVI, PI, ORI). After the anesthesia induction and tarakeal entubation, first twenty patient will take 300 mL fresh gas flow with AGC mode (group 1), Second twenty patient will take 600 mL fresh gas flow with AGC mode (group 2), third twenty patient will take 600 mL fresh gas flow with manually. Hemodynamic and gas consumption data will be recorded. An operating room will be reserved for this study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: March 1, 2021
• Est. primary completion date: October 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Adult patients undergoing hepatectomy with general anesthesia

Exclusion Criteria:

• Essential data missing

• Patient participating in other research projects

• Drug allergy

• Anesthetic complication story

Related Conditions & MeSH terms

• Safety Issues

Locations

Country	Name	City	State
Turkey	Inonu Univercity	Malatya

Sponsors (1)

Lead Sponsor	Collaborator
Inonu University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Amount of used anesthetic gas (desflurane)	Amount of used desflurane will be determined in milliliter by anesthesia machine (Maquet Flow i40) for each patient.	Through study completion, an average of 2 month
Secondary	Heart rate	Heart rate/min	Through study completion, an average of 2 month
Secondary	Mean arterial pressure	Mean arterial pressure (mm/Hg)	Through study completion, an average of 2 month
Secondary	Peripheral oxygen saturation	Peripheral oxygen saturation (%)	Through study completion, an average of 2 month