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Rupture clinical trials

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NCT ID: NCT05430711 Not yet recruiting - Clinical trials for Prelabor Rupture of Membranes

Dinoprostone Induction vs. Expectant Management After PROM at Term

Start date: June 2022
Phase: Phase 4
Study type: Interventional

Prelabour rupture of membranes (PROM) is associated with intrauterine infection and maternal and neonatal consequences. This risk increases with the length of time from PROM to delivery. Induction of labor has been shown to reduce the rates of those complications, however the optimal time interval has not yet been determined. The main purpose of this single-center randomized prospective study is to assess the differences between two approaches of managing PROM at term-expectant management and induction with a dinoprostone vaginal delivery system.

NCT ID: NCT05420974 Not yet recruiting - Meniscus Rupture Clinical Trials

NIR Arthroscopic Fluorescence Angiography of Menisci

FLUORarth
Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This trial is an explorative single center, single-arm study to assess whether vascularization of the meniscus can be visualized intraoperatively using arthroscopic near-infrared (NIR) fluorescence using ICG during standard of care meniscal repair treatment.

NCT ID: NCT05413213 Not yet recruiting - Shoulder Pain Clinical Trials

Ambulatory Rehabilitation Program in Patients With Degenerative Rupture of the Rotator Cuff Tendons of the Shoulder

ERARC
Start date: September 2022
Phase: N/A
Study type: Interventional

The main objective of the research is to study the effectiveness of an ambulatory rehabilitation program based on mobilization and muscular solicitation, during painful shoulders by full-thickness degenerative rupture of the tendons of the rotator cuff. , with the algo-functional state, ie pain and activity limitation, as judgment criteria, at 3 months.

NCT ID: NCT05375071 Not yet recruiting - Clinical trials for Patellofemoral Joint Dislocation

BFR After Biceps Tendon Repair and MPFLR

Start date: May 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of utilizing blood flow restriction (BFR) therapy after distal biceps tendon repair or medial patellofemoral ligament reconstruction (MPFLR) following a tear.

NCT ID: NCT05328817 Not yet recruiting - Clinical trials for Preterm Premature Rupture of Membrane

Azithromycin Versus Erythromycin For Preterm Prelabor Rupture of Membranes

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Aim 1. To examine the latency period according to antibiotic regimens (erythromycin iv for two days followed by orally for 5 days vs. azithromycin iv for 2 days followed by 5 days orally). Aim 2. To examine the latency period according to races stratified by antibiotic regimens. Aim 3: To examine if there is a difference in neonatal morbidity and mortality stratified by antibiotic regimen.

NCT ID: NCT05279274 Not yet recruiting - Clinical trials for Abdominal Aortic Aneurysm Without Rupture

ShorT Stay Aneurysm Repair Study

STAR
Start date: November 1, 2022
Phase:
Study type: Observational

A prospective observational cohort study to assess the eligibility, uptake, viability, acceptability, safety, and cost of a ShorT stay (23-hour) Aneurysm Repair (STAR) pathway. Outcomes will be collected for up to 1 year.

NCT ID: NCT05207800 Not yet recruiting - Clinical trials for Preterm Premature Rupture of Membrane

Predictive Value of Maternal Serum Pentraxin 3 (PTX 3) and Heparin-binding Protein (HBP) for Chorioamnionitis in Preterm Premature Rupture of Membranes

Start date: February 10, 2022
Phase:
Study type: Observational

Objective: The aim of this study was to investigate the predictive value of maternal serum pentraxin 3 (PTX3) and heparin-binding protein (HBP) for chorioamnionitis in preterm premature rupture of membranes (PPROM). Method: This observational prospective cohort study included a total of 180 pregnant women at 24-40 gestational weeks. There were 60 cases of term premature rupture of membranes (TPROM), 60 cases of preterm premature rupture of membranes(PPROM)and 60 cases of healthy women. The concentrations of PTX3 and HBP were measured in maternal blood and amniotic fluid using an enzyme-linked immunosorbent assay (ELISA). Western immunoblotting was used to analyze the expression of PTX3 and HBP in placental tissue. The localization and immunoreaction of PTX3 and HBP in placenta were determined via immunohistochemistry (IHC).

NCT ID: NCT05134688 Not yet recruiting - Clinical trials for Premature Rupture of Membrane

Magnesium Sulphate in Premature Rupture of Membranes

Start date: May 30, 2022
Phase: Early Phase 1
Study type: Interventional

To assess the outcome of using magnesium sulphate on fetus and women with preterm premature rupture of membranes

NCT ID: NCT05095415 Not yet recruiting - Clinical trials for Distal Radius Fracture

Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting

Start date: October 2021
Phase: N/A
Study type: Interventional

This will be a prospective randomized control trial with a blocking method to determine the effect of an occupational therapy focused pre-operative education on 3 pre-determined diagnosis: Carpometacarpal (CMC) Arthroplasty, Distal radius fracture requiring open reduction internal fixation (ORIF) and tendon repairs of the hand. Possible participants will be recruited through Cape Fear Orthopedics & Sports Medicine and receiving care from an orthopedic surgeon & hand specialist. Researchers hypothesize that those who receive the occupational therapy consult will demonstrate improved adherence with occupational therapy appointments, improved patient perceived function, and overall improved experiences with the pre-operative patient experience.

NCT ID: NCT05060900 Not yet recruiting - Hand Injuries Clinical Trials

Hand Ligament Reconstructions With Knee Collateral Ligament Allografts

Start date: September 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to review the clinical outcomes following hand ligament reconstruction surgery using allograft (cadaveric) knee collateral ligaments. Currently, there is no standard procedure or devices used for hand ligament reconstruction surgery, although most techniques use some form of autograft (patients' own tissue) for the reconstruction. We believe that the use of allograft ligaments in reconstruction may eliminate the pain associated with procuring the patients' own tissue for the procedure, and prove to be a viable and preferred alternative to the multiple techniques currently used. The main procedures of this study include wrist and hand ligament reconstruction surgery (for wrist scapholunate (SL) ligaments, thumb ulnar collateral ligaments (UCL), and finger proximal interphalangeal (PIP) joint collateral ligaments) using allograft ligament, and subsequent follow up appointments where measurements and questionnaires will be completed to evaluate how hand function is doing after surgery.