A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular

Rupture, Spontaneous Clinical Trial

Official title:

A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular Carcinoma: A Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03504358
• Other study ID #: Zhupeng002
• Status: Completed
• First received: April 4, 2018
• Last updated: April 12, 2018
• Start date: January 1, 2005
• Est. completion date: December 31, 2017

Study information

• Verified date: April 2018
• Source: Huazhong University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Develop a new scoring system for HCC patients with tumor rupture.

Description:

There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 129
• Est. completion date: December 31, 2017
• Est. primary completion date: May 1, 2015
• Gender: All
• Age group: 15 Years to 75 Years

Eligibility

Inclusion Criteria:

• Received partial hepatectomy; with Child A or B liver function.

Exclusion Criteria:

• Without complete data;loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.

Related Conditions & MeSH terms

• Carcinoma, Hepatocellular
• Rupture
• Rupture, Spontaneous

Intervention

Procedure:
• Liver resection
Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Huazhong University of Science and Technology

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overall survival	Overall survival after partial hepatectomy	3 years
Secondary	Disease-free survival	Recurrence-free survival after partial hepatectomy	3 years