Clinical Trials Logo

Clinical Trial Summary

Rumination is an upper gastrointestinal (GI) disorder characterized by the frequent regurgitation of recently ingested food. Very little is understood about the nature and treatment of this disorder. The act of regurgitation in rumination involves the opening of the upper esophageal sphincter and the muscular contraction of the abdomins rectus. Behavioral treatment of these symptoms is the clinical intervention of choice; however, only uncontrolled case documentation exists to support its effectiveness. However, an effective behavioral mechanism may be relaxation of the muscles. From a behavioral standpoint, muscular relaxation is incompatible with the necessary muscular contraction for rumination.

To date, single case documentation and few designed single case studies have examined the clinical effectiveness of behavioral interventions for GI rumination. In the current study, the investigators seek to examine the effectiveness of two behavioral relaxation interventions for GI rumination through a treatment as usual paradigm (proposed N = 20). Our primary goals are to examine the clinical effectiveness of these interventions in symptom reduction at 1- and 3-month follow-up.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01576302
Study type Interventional
Source Mayo Clinic
Contact
Status Completed
Phase Phase 3
Start date April 2012
Completion date December 2014

See also
  Status Clinical Trial Phase
Terminated NCT04367636 - The Effects of Attention Training on Emotion Regulation and Stress Related Complaints During COVID-19 N/A
Completed NCT04933734 - Turkish Cultural Adaptation, Validity and Reliability of the "Physical Activity-Specific Rumination Scale for Children"
Recruiting NCT03724305 - Reduce Emotional Symptoms of Insomnia With SleepTreatment N/A
Completed NCT01983033 - Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission N/A
Completed NCT05027113 - App-Based Mindfulness Meditation for People of Color Who Experience Race-Related Stress N/A
Completed NCT05589116 - An Online Compassionate Imagery Intervention for Veterinarian Mental Health N/A
Active, not recruiting NCT05590741 - An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy N/A
Recruiting NCT04697966 - Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents N/A
Recruiting NCT05350007 - Evaluation of Rumination, Frailty and Tanatophobia in Cancer Patients Over 65 Years of Age
Recruiting NCT05353231 - Brief Mental Training and Internal Attentional Control N/A
Not yet recruiting NCT06226467 - Neurobehavioral Affective Control Training N/A
Recruiting NCT05344820 - The Effect of the Art-based Mandala Intervention on the Quality of Life of Cancer Patients Receiving Chemotherapy N/A
Completed NCT05390879 - Influence of Meditation on Stress and Rumination Following Objective Structured Clinical Examination (OSCE) N/A
Completed NCT03915041 - Effects of tDCS Combined With VR on Anxious Ruminations in Healthy Subjects With a Vulnerability to Rumination N/A
Completed NCT04950257 - Evaluating the Effects of a Self-help Mobile Phone Application on Worry and Overthinking in Young Adults Aged Between 16 and 24. N/A
Completed NCT03912636 - Role of Vagal Tone in Rumination Syndrome N/A
Active, not recruiting NCT03322774 - Sleep To Reduce Incident Depression Effectively N/A
Completed NCT04567888 - Testing a Digital Intervention for Adolescents N/A
Completed NCT03900416 - Adolescent Mindfulness Mobile App Study (RCT) N/A
Completed NCT03487081 - Neural Predictors of Social Emotion Regulation Training N/A