Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections

Status Not yet recruiting

Clinical Trial Summary

The purpose of this study is to compare the functional outcomes of patients with shoulder pathology treated with either ketorolac or corticosteroid injections, in a randomized double-blinded study. Investigators will compare the effectiveness of ketorolac compared to corticosteroid. Specific Aim 1: Hypothesis 1: Injection of the shoulder (in the subacromial space) with Ketorolac will be more effective than corticosteroid injection for the treatment of a variety of shoulder pathologies. The risks associated with this study primarily concern adverse reactions to the study drugs. The drugs used in this study are not narcotics or habit-forming but can have side effects. The patient's physician will screen for any heart, intestinal, or kidney disease or condition that would increase the chance for the patient to have an unwanted side effect.

Clinical Trial Description

The proposed study is a three arm, double-blinded, prospective randomized controlled clinical trial with follow-up immediately after the injection and at day 2, and weeks 1, 2, 4, 6, and 12. In this study investigators will compare the effectiveness of ketorolac compared to corticosteroid. Subjects being seen for a rotator cuff injury will be randomized into one of three treatment groups pertaining to their pathology. The intervention will begin once the subject has consented and answered the Baseline Outcome Shoulder Questionnaire. The Baseline Outcome Questionnaire consists of the Visual Analog Score, American Shoulder and Elbow Score, Single Assessment Numeric Evaluation, Pittsburgh Sleep Quality Index, Short Form-12, and questions pertaining to patient characteristics, injury characteristics, co-morbidities, patient history, medications, and demographics. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04895280
Study type	Interventional
Source	University of Texas Southwestern Medical Center
Contact	Cynthia Wright
Phone	214-645-0423
Email	Cynthia.Wright@UTSouthwestern.edu
Status	Not yet recruiting
Phase	Phase 4
Start date	April 2024
Completion date	November 2028

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT03319784` - Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients	Phase 4
Not yet recruiting	`NCT06023914` - Analysis of the Effect of Neuromuscular Electro-stimulation on the Performance of Isometric Rotator Cuff Strength.	Phase 2/Phase 3
Completed	`NCT01984203` - Rotator Cuff Tendinopathy Exercise Trial	N/A
Completed	`NCT01402011` - Study of 25% Dextrose Injections in Shoulder Ligaments and Tendons to Promote Their Healing	N/A
Completed	`NCT01355549` - Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury	Phase 1
Terminated	`NCT00764764` - Study of the Effect of Neck Treatment on Shoulder Impingement	Phase 1
Completed	`NCT03892603` - Does The Type of Exercise Influence Outcome in Rotator Cuff Related Shoulder Pain	N/A
Active, not recruiting	`NCT03752827` - Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears	N/A
Recruiting	`NCT05264935` - Ultrasound-guided Lavage of Calcific Deposits of the Rotator Cuff
Recruiting	`NCT02967640` - Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?	Phase 2/Phase 3
Terminated	`NCT04115644` - Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial	Phase 4
Completed	`NCT03425357` - Sonoelastography of the Supraspinatus Tendon	N/A
Completed	`NCT03425344` - Discriminative Validity of Strain Elastography of the Supraspinatus Tendon	N/A
Recruiting	`NCT04923477` - Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms	N/A
Not yet recruiting	`NCT06372600` - Effect of Extracorporeal Shock Wave Combined With Autologous Platelet-rich Plasma Injection on Rotator Cuff Calcific Tendinitis	N/A
Completed	`NCT06425913` - Effects of Cold and Kinesio Taping in Individuals With Rotator Cuff Tendonitis	N/A
Completed	`NCT03675399` - Effect of Isometric Exercise on Pain Perception in Rotator Cuff Related Shoulder Pain	N/A
Recruiting	`NCT05489484` - Performance and Safety Evaluation of MD-Shoulder Collagen Medical Device in the Treatment of Rotator Cuff Syndrome	N/A
Recruiting	`NCT04094298` - Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease	Phase 3
Active, not recruiting	`NCT03167138` - Micro-Fragmented Adipose Tissue (Lipogems®) Injection for Chronic Shoulder Pain in Persons With Spinal Cord Injury	Early Phase 1