Rotator Cuff Tear Clinical Trial
Official title:
Autologous Pure Platelet-rich Plasma in the Treatment of Tendon Diseaseļ¼A Randomized Controlled Trial
This is a randomized parallel controlled double-blind phase 2 clinical study.All subjects are recruited from the patients of rotator cuff tear, lateral epicondylitis or chronic achilles tendonitis. Patients will be randomly divided into three groups. Autologous pure platlet-rich plasma (P-PRP) and platlet-rich plasma (PRP) are purified from the peripheral blood .Patients of case groups will receive P-PRP or PRP injection once a week for three times while the control group received the same dose compound betamethasone injection. Follow up visit will occur at 1 month,3 months, 6 months,12 months after the last injection. Clinical quantitative assessment will measure by the visual analogue scale(VAS). The secondary outcomes are the constant-murley score(CMS) and the rating scale of the American shoulder and elbow surgeons(ASES) and the disability of arm shoulder and hand(DASH). The objective evaluation methods is that the examination of MRI or ultrasound were accomplished before the first injection and at 6 and 12 months afterwards.
All injection will be done under ultrasound guidance. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03663036 -
Arthroscopic Superior Capsular Reconstruction With Fascia Lata Autograft - Survivorship of the Autograft Analysis
|
N/A | |
| Withdrawn |
NCT03319784 -
Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients
|
Phase 4 | |
| Suspended |
NCT03290196 -
The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics
|
Phase 4 | |
| Active, not recruiting |
NCT03091075 -
Oxandrolone Rotator Cuff Trial
|
N/A | |
| Completed |
NCT03380533 -
Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair
|
Phase 2/Phase 3 | |
| Completed |
NCT04566939 -
A Long Term Follow-Up of Rotator Cuff Tear Patients Treated With Integrated Complementary and Alternative Medicine
|
||
| Active, not recruiting |
NCT02716441 -
Rotator Cuff Failure With Continuity
|
||
| Completed |
NCT03540030 -
Opioid-Free Shoulder Arthroplasty
|
Phase 4 | |
| Completed |
NCT02298023 -
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
|
Phase 2 | |
| Completed |
NCT01383239 -
Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs
|
N/A | |
| Completed |
NCT01459536 -
Assessment of Muscle Function and Size in Older Adults With Rotator Cuff Tear
|
N/A | |
| Completed |
NCT02850211 -
A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair
|
Phase 4 | |
| Completed |
NCT01170312 -
Arthroscopic Surgery and Platelet Rich Plasma In Rotator Cuff Tear Evaluation
|
N/A | |
| Terminated |
NCT00936559 -
Study Evaluating Safety Of BMP-655/ACS As An Adjuvant Therapy For Rotator Cuff Repair
|
Phase 1 | |
| Completed |
NCT01204606 -
Arthroscopic Rotator Cuff Repair With Multimodal Analgesia(MMA)
|
N/A | |
| Completed |
NCT00852657 -
Comparison of Tendon Repair and Physiotherapy in the Treatment of Small and Medium-sized Tears of the Rotator Cuff
|
N/A | |
| Active, not recruiting |
NCT00182299 -
An RCT to Compare the Outcomes of Patients With Large Rotator Cuff Repair That Undergo Repair With or Without SIS
|
Phase 4 | |
| Recruiting |
NCT06120998 -
Quality of Life After Arthroscopic Rotator Cuff Repair
|
||
| Completed |
NCT05897866 -
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM)
|
N/A | |
| Completed |
NCT02644564 -
Early Clinical Examination and Ultrasonography Screening of Acute Soft Tissue Shoulder Injuries
|
N/A |