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Rosacea clinical trials

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NCT ID: NCT04336163 Terminated - Rosacea Clinical Trials

Skin Imaging to Inform Laser Treatments

Start date: September 20, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to obtain information (such as lesion depth, depth of the most superficial part of the lesion, and the size and density of blood vessels) with the assistance of an imaging device, and use this information to assist in selection of laser settings for the treatment of skin conditions. The imaging modality is called Optical Coherence Tomography (OCT). Multiple laser modalities will be used, including intense pulsed light lasers (BroadBand Light, Profractional Sciton), pulsed dye lasers (Vbeam Perfecta, Candela), long-pulse 755nm lasers (GentleLASE, Candela), Sciton long-pulse 1064nm lasers, and non-ablative and ablative fractional resurfacing lasers (Profractional, Sciton). All of the lasers noted above are the only ones that will be used in this study. These lasers have 510k clearance and are being used as per their approved indications in this study. The choice of laser type is based on the skin lesion and is recommended by the physician, and the subjects who are going to enroll in this study will already be planned to undergo laser treatment as a standard of care for their condition. This is a pilot study that will explore the utility of skin imaging in guiding the laser treatment of skin lesions.

NCT ID: NCT03708263 Terminated - Clinical trials for Erythematotelangiectatic Rosacea

Evaluation of the New Laser PHOTOLASE PLV-585nm for the Treatment of Rosacea

ROSAPHOTOLASE
Start date: September 8, 2020
Phase: N/A
Study type: Interventional

Rosacea is a frequent dermatological condition, with a chronic and disturbing evolution that is characterized by redness, permanent erythema associated with telangiectasia (visible and permanent dilatation of the small vessels). It frequently affects men and women with fair skin and can have significant psycho-emotional consequences. To counteract the unaesthetic appearance of redness and eliminate telangiectasia, the use of the laser is proposed to the patient. This study is a single center prospective, randomized, controlled split face study to compare 532nm KTP laser versus 585 nm PLV Laser in terms of improvement of the symptoms in the treatment of Erythematotelangiectatic Rosacea 20 subjects will receive up to 3 laser treatments at day 0, month 2 and 4 and will be followed at month 6 and 12.

NCT ID: NCT03564145 Terminated - Clinical trials for Papulopustular Rosacea

A Long-Term Safety Study of S5G4T-1 in the Treatment of Papulopustular Rosacea

Start date: September 12, 2018
Phase: Phase 3
Study type: Interventional

To assess the safety of S5G4T-1 when applied once daily for up to 40 weeks in participants with papulopustular rosacea who completed either Study SGT-54-01 (NCT03448939) or Study SGT-54-02 (NCT03564119).

NCT ID: NCT03508869 Terminated - Clinical trials for Erythema and Flushing Associated With Rosacea

Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea

Start date: September 27, 2016
Phase: N/A
Study type: Interventional

To evaluate the safety and efficacy of Mirvaso® Gel and Dysport® for erythema and flushing of Rosacea.

NCT ID: NCT01134991 Terminated - Rosacea Clinical Trials

Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Rosacea Patients

Start date: June 2010
Phase: Phase 2
Study type: Interventional

Acne rosacea is a chronic acneiform disorder affecting both the skin and the eye. It is a syndrome of undetermined etiology characterized by both vascular and papulopustular components involving the face and occasionally the neck and upper trunk. This is a pilot phase II study to evaluate the tolerability and safety and to monitor the clinical efficacy of Topical Minocycline Foam FXFM244 in moderate to severe Rosacea patients.

NCT ID: NCT01125930 Terminated - Rosacea Clinical Trials

Atralin Gel for the Treatment of Rosacea

Start date: May 2010
Phase: Phase 3
Study type: Interventional

Erythematotelangiectatic rosacea is a type of rosacea that causes a red face often with frequent flushing, topical sensitivity and prominent blood vessels. We think that long term damage to skin from the sun (photodamage) may play a role in causing this type of rosacea. Tretinoin is a topical medication that is known to improve photodamage. We want to find out if Atralin (tretinoin 0.05%) Gel used for up to 46 weeks will improve erythematotelangiectatic rosacea (ETR).

NCT ID: NCT00395226 Terminated - Rosacea Clinical Trials

Zinc Sulfate in the Treatment of Rosacea: A Randomized, Controlled Trial

Start date: July 2006
Phase: N/A
Study type: Interventional

Rosacea is a common chronic dermatological condition, characterized by recurrent or persistent redness, permanent dilation of small blood vessel causing small red lesions, and papules/pustules. The signs of rosacea are usually confined to the face, but may appear on the neck, scalp or trunk. Opthalmologic findings are also common. Rosacea is usually described as being most common in fair skinned women over 40. The purpose of the study is to determine whether oral Zinc Sulfate treatment is an effective treatment for facial rosacea.