Clinical Trials Logo

Clinical Trial Summary

Correct assessment of right ventricular function by transthoracic echocardiographic examination in pediatric patients with congenital valvular pulmonary stenosis after Percutaneous Balloon Pulmonary Valvuloplasty


Clinical Trial Description

The right ventricle plays an important role in the morbidity and mortality of patients presenting with signs and symptoms of cardiopulmonary disease. However, the systematic assessment of right heart function is not uniformly carried out. This is due partly to the enormous attention given to the evaluation of the left heart, a lack of familiarity with ultrasound techniques that can be used in imaging the right heart, and a paucity of ultrasound studies providing normal reference values of right heart size and function. In patients with CHD, the right ventricle (RV) may function as either the sub-pulmonary or the systemic ventricle as in transposition of great arteries (TGA). CHD more commonly affecting the right heart includes atrial septal defects (ASD), Tetralogy of Fallot (TOF), pulmonary stenosis (PS), Ebstein anomaly, arrhythmogenic right ventricular cardiomyopathy (ARVC), and pulmonary valve atresia. In many of these patients, prevention of "irreversible" right heart failure (RHF) will require timely corrective surgery or when not possible, surgical palliation . Congenital pulmonary valve stenosis is a common congenital heart disease. Isolated pulmonary valve stenosis comprises 8-10% of all congenital heart disease . While surgical pulmonary valvotomy has been available as a treatment since 1956, it requires a median sternotomy, use of cardiopulmonary bypass, and post-surgical ICU admission with multi-day hospitalization. Recognizing the potential advantages of a less invasive approach, the first attempts at percutaneous catheter-based dilation of stenotic pulmonary valves were performed in the 1950s. As the technique was refined and catheter and balloon technology have advanced, the results of balloon pulmonary valvuloplasty have improved and the approach has become the standard of care for treating pulmonary valve stenosis ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04960085
Study type Observational
Source Assiut University
Contact Saad Abdelhafiz Abdelsalam, master degree
Phone 01007459576
Email saadabdelsalam13@gmail.com
Status Not yet recruiting
Phase
Start date July 2, 2021
Completion date August 2, 2022

See also
  Status Clinical Trial Phase
Completed NCT03183414 - Right Ventricular Dysfunction in Cardiac Surgery Patients
Recruiting NCT04764032 - Right Ventricular Dysfunction in Ventilated Patients With COVID-19
Not yet recruiting NCT05188222 - Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery Phase 4
Not yet recruiting NCT06002321 - Right Ventricular Dysfunction in Chronic Heart Failure
Completed NCT05948332 - Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation
Recruiting NCT03309852 - Emergency Department Assessment of Right Ventricular Function and Size in the Post Cardiac Arrest Patient
Recruiting NCT05583461 - Ventilator-induced Right Ventricular Injury During EIT-based PEEP Titration in Patients With ARDS N/A
Completed NCT03438825 - PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients
Active, not recruiting NCT01230294 - New Echocardiographic Methods for Right Ventricular Function. N/A
Completed NCT00557934 - Right Ventricular Contractility Reserve Following Repair of Tetralogy of Fallot N/A
Completed NCT04694378 - Relationship Between Strain and Stroke Volume in Cardiac Surgery
Not yet recruiting NCT04167241 - Right Ventricle Function After Major Right Lung Resection
Recruiting NCT03013075 - General Plus Spinal Anesthesia and General Anesthesia Alone on Right Ventricular Function Phase 4
Completed NCT06197256 - Cardiac Dysfunction in Critically Ill Covid-19 Patients
Completed NCT03301571 - Right Ventricular Echocardiography in caRdiac SurgEry N/A
Recruiting NCT05860504 - Acute Cardiac Dysfunction in Critical Illnes
Completed NCT01093001 - Tricuspid Regurgitation Study Phase 4
Recruiting NCT05758194 - Mitigating Post-Op RV Dysfunction After LVAD Implantation N/A
Not yet recruiting NCT05768230 - Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV Phase 2/Phase 3
Not yet recruiting NCT05620992 - Evaluation of Right Ventricular Function Post Mitral Valve Operations