Right Ventricular Dysfunction Clinical Trial
Official title:
Evaluation of New Echocardiographic Methods for Measurement of Right Ventricular Function.
Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and strain-echocardiography) for measurement of the right ventricular (RV) function .
Studies of the last years revealed that the right ventricular function is an important
predictive value for the survival of patients with congenital heart disease, pulmonary
hypertension or chronic heart failure. In 2006 the National Heart, Lung and Blood Institute
has pronounced the right ventricular dysfunction including the non-invasive assessment of
the right ventricular function as preferential aim of cardiovascular research.
Many parameters are used to describe right ventricular dysfunction, but none of these has a
comparable significance like the left ventricular ejection fraction. Because of the
limitation of each right ventricular parameter the stepwise combination of these parameters
is used to describe right ventricular function what frequently results in further problems,
especially in comparison of long-term controls.
Aims of this study are the evaluation of new echocardiographic methods (3D/4D- and
strain-echocardiography) for measurement of the right ventricular (RV) function. The study
is carried out as prospective, monocentric trial at the Department of Cardiology of the
University Hospital of Heidelberg. Three different groups are set up for the assessment of
the right ventricular function: patients with pulmonary arterial hypertension, patients with
chronic heart failure of the left ventricle affecting the right heart and patients without
structural heart disease who underwent an echocardiographic examination for other reasons
(control group).
All participants are re-examined in constant intervals as clinically indicated.
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Observational Model: Case Control, Time Perspective: Prospective
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