The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without Platelet Rich Fibrin( PRF)

Ridge Deficiency Clinical Trial

Official title:

The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without PRF In Conjunction With Simultaneous Implant Placement In Narrow Alveolar Ridges: A Randomized Controlled Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03037125
• Other study ID #: PERIO 3:7:3
• Status: Completed
• Phase: N/A
• Start date: March 1, 2017
• Est. completion date: June 1, 2019

Study information

• Verified date: May 2024
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Split crest technique is a technique for horizontal bone augmentation used in case of narrow alveolar ridges as an alternative to the more aggressive techniques such as onlay bone grafting, guided bone regeneration (GBR) and distraction osteogenesis

The study goal is to evaluate whether if there will be any benefit of using platelet rich fibrin (PRF) with the split crest technique regarding bone width gain and healing response in comparison with split crest technique alone, where PRF is considered an autologous, growth factor containing material which is easy to collect and is of low cost.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: June 1, 2019
• Est. primary completion date: March 15, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 70 Years

Eligibility

Inclusion Criteria:

1. Patients with at least one missing tooth in the maxillary region

2. All the selected patients have a bucco-palatal width of the edentulous alveolar ridge from 3.5-5.5mm.

3. All the selected patients have at least 12 mm residual bone height at the edentulous area

4. The recipient site of the implant should be free from any pathological conditions.

5. No diagnosed bone disease or medication known to affect bone metabolism.

6. Patients who are cooperative, motivated, and hygiene conscious.

Exclusion Criteria:

1. Patients unable to undergo minor oral surgical procedures.

2. Patients with a history of drug abuse or catabolic drugs.

3. Patients with a history of psychiatric disorder.

4. Patients with unrealistic expectations about the esthetic outcome of implant therapy.

5. Patients with insufficient vertical inter-arch space, upon centric occlusion, to accommodate the available restorative components.

6. Patients in the growth stage with partially erupted teeth.

7. Patients who have any systemic condition that may contraindicate implant therapy.

8. Patients who have any habits that might jeopardize the osseointegration process, such as smoking and alcoholism.

9. Patients with parafunctional habits that produce overload on the implant, such as bruxism and clenching.

Related Conditions & MeSH terms

• Ridge Deficiency

Intervention

Procedure:
• Split Crest with PRF
Narrow ridges are split to increase the ridge width and immediate implants are placed with PRF closing the gap
• Split Crest without PRF
Narrow ridges are split to increase the ridge width and immediate implants are placed without grafting

Locations

Country	Name	City	State
Egypt	Faculty of oral and dental medicine, Cairo university	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Bone width gain		6 months