Clinical Trials Logo

Clinical Trial Summary

This study is sponsored by Sierra Oncology, Inc. formerly ProNAi Therapeutics, Inc. It is a multi-center, single-arm, 2-stage, open-label phase II investigation of PNT2258 to characterize anti-tumor activity and collect safety data on patients with Richter's Transformation.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02378038
Study type Interventional
Source Sierra Oncology LLC - a GSK company
Contact
Status Terminated
Phase Phase 2
Start date August 2015
Completion date June 2016

See also
  Status Clinical Trial Phase
Terminated NCT02138786 - Selinexor in Initial or Refractory and/or Relapsed Richter's Transformation Phase 2
Terminated NCT03153514 - Obinutuzumab Containing Conditioning Regimen for Patients With Poor Risk CLL or Richter's Transformation Requiring Allogeneic Stem Cell Transplantation Phase 2
Completed NCT00472849 - Oxaliplatin, Fludarabine, Cytarabine, and Rituximab in Patients With Richter's Transformation and Leukemias Phase 1/Phase 2
Recruiting NCT05294731 - Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader Phase 1/Phase 2
Active, not recruiting NCT03162536 - A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001) Phase 1/Phase 2
Terminated NCT03121534 - Ibrutinib, Nivolumab and Blinatumomab in Richter Transformation Phase 2
Recruiting NCT06043674 - A Ph 2 Study of Glofitamab Alone or in Combination With Polatuzumab Vedotin or Atezolizumab in Richter's Transformation Phase 2
Completed NCT01217749 - Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLL Phase 1/Phase 2
Recruiting NCT04305444 - Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas Phase 2
Active, not recruiting NCT04806035 - Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia Phase 1
Terminated NCT03778073 - Study of Cosibelimab in Subjects With Relapsed or Refractory Lymphoma Phase 1