Rhinoplasty Clinical Trial
Official title:
The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism
This is a prospective observation cohort investigation. Patients, that is participants, undergoing primary functional rhinoplasty will be evaluated in terms of measuring capillary blood lactic acid concentration in the nasal skin-soft tissue envelope immediately after the procedure and 7 days after the procedure. The aim of our study is to test whether or not different rhinoplasty approaches and volume of the used autologous cartilage grafts impact the nasal skin-soft tissue metabolism.
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | September 1, 2026 |
Est. primary completion date | January 2, 2026 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Adult patients undergoing primary functional rhinoplasty who comply with the study - Adult patients undergoing primary functional rhinoplasty who have singed the informed consent, previously approved by the ethics commitee. Exclusion Criteria: - - patients with previous surgical procedures to the nose - patients with greater previous injury or burns to the nasal skin - patients with autoimmune skin conditions - patients with significant cardiovascular diseases - patients unwilling to comply with the study - patients who do not want to sign the informed consent, previously approved by the ethics commitee. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
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University Hospital "Sestre Milosrdnice" |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Difference of capillary blood lactic acid concentration in the nasal skin-soft tissue envelope depending on the rhinoplasty approach | In participants undergoing primary functional rhinoplasty, the capillary blood lactic acid concentration from the skin-soft tissue envelope will be assessed by using Statstrip lactate measuring device and Statstrip test strips immediately after the procedure and 7 days after the procedure. | immediately after the surgical procedure and 7 days after the procedure | |
Primary | Correlation between the used autologous cartilage graft volume and lactic acid concentration in the nasal skin-soft tissue envelope | In the same participants undergoing different rhinoplasty approach, the volume of the used autologous cartilage grafts will be measured by using water displacement method, and this result will be correlated with the capillary blood lactic acid concentration from the skin-soft tissue envelope. | immediately after the surgical procedure and 7 days after the procedure |
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