Rhinoconjunctivitis Clinical Trial
Official title:
An Optional Investigation of Biomarkers of Efficacy in TH002 Clinical Study Subjects.
House Dust Mites (HDM) are arachnids that infest bedding, carpet, upholstered furniture and
fabric. Like many other allergens, exposure to HDMA in sensitised patients is associated
with poorer lung function, greater medication requirements and more asthma symptoms as well
as chronic rhinosinusitis symptoms. In contrast to other allergens, there is evidence that
HDMA leads to the development of asthma, in addition to exacerbating pre-existing asthma in
HDM-sensitised patients.
ToleroMune House Dust Mite (TM-HDM) is being developed for the treatment of HDM allergy.
Study TH002 evaluated the efficacy, safety and tolerability of TM-HDM. This study will
identify cellular, proteomic or genetic biomarkers of efficacy to TM-HDM treatment in TH002
study participants
n/a
Observational Model: Cohort, Time Perspective: Prospective
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