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Clinical Trial Summary

The study evaluates the safety and effect of intralymphatic allergen specific immunotherapy in increasing doses. Patients that have already undergone subcutaneous immunotherapy will be treated with three intralymphatic injections in increasing doses; 1000 SQ-U, 3000 SQ-U and 10 000 SQ-U, or placebo.


Clinical Trial Description

38 patients with seasonal allergic rhinitis that have recently (within 20 months) ended a full subcutaneous immunotherapy protocol with birch or grass allergen with improvement but not full symptom relief are recruited. Study subjects are randomized to intralymphatic injections with placebo or ALK Alutard 5-grasses or birch. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02679105
Study type Interventional
Source Karolinska Institutet
Contact
Status Completed
Phase Phase 2/Phase 3
Start date May 2015
Completion date March 2019

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