Rheumatoid Arthritis Clinical Trial
Official title:
Clinical Study of 18F-labeled Probes Targeting Fibroblast Activating Protein and Integrin avĪ²3 (FAPI-RGD) to Assess Disease Activity in Rheumatoid Arthritis
| NCT number | NCT05944198 |
| Other study ID # | SichuanPPH-RA |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | July 14, 2023 |
| Est. completion date | February 2024 |
| Verified date | January 2024 |
| Source | Sichuan Provincial People's Hospital |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational [Patient Registry] |
The goal of this observational study is to learn about 18F-FAPI-RGD PET/CT imaging in assessing rheumatoid arthritis disease activity. Participants will undergo clinical evaluation and 18F-FAPI-RGD PET/CT examination.
| Status | Recruiting |
| Enrollment | 30 |
| Est. completion date | February 2024 |
| Est. primary completion date | February 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | N/A and older |
| Eligibility | Inclusion Criteria: - Patients with rheumatoid arthritis who meet the 2010 American College of Rheumatology/European League Against Rheumatism Rheumatoid arthritis classification criteria. Exclusion Criteria: - A. Patients with malignant tumors and other rheumatic immune diseases; B. clinical and conventional radiographic inspection of materials; C. researchers think not suitable for other information to participate in this study. |
| Country | Name | City | State |
|---|---|---|---|
| China | Departments of Nuclear Medicine, Sichuan Provincial People's Hospital | Chengdu | Sichuan |
| Lead Sponsor | Collaborator |
|---|---|
| Sichuan Provincial People's Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Correlation between clinical indicators and PET/CT results | Correlation of clinical disease activity Index (cDAI), erythrocyte sedimentation rate (ESR), and CRP levels with 18F-FAPI-RGD PET/CT results | 1 month |
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