Rheumatoid Arthritis Clinical Trial
— RASGENASOfficial title:
Rheumatoid Arthritis Susceptibility Genes in Austrian and Slovak Population
Verified date | February 2013 |
Source | Slovak Academy of Sciences |
Contact | n/a |
Is FDA regulated | No |
Health authority | Slovak Republic: Ethics Committee |
Study type | Observational |
The study is aimed at revealing genetic background in rheumatoid arthritis (RA). For that purpose samples of DNA will be collected from 500 RA patients and similar number of controls from whole Slovakia. Variations in several genes associated with RA will be evaluated. The second aim is to assess functional changes in immune cells from selected patients and their evaluation together with genetic background. The project has observational character without any intention to change the treatment of RA patients.
Status | Completed |
Enrollment | 790 |
Est. completion date | December 2012 |
Est. primary completion date | June 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - rheumatoid arthritis or healthy Exclusion Criteria: |
Observational Model: Case Control, Time Perspective: Cross-Sectional
Country | Name | City | State |
---|---|---|---|
Slovakia | Slovak Academy of Sciences, Center for Molecular Medicine | Bratislava |
Lead Sponsor | Collaborator |
---|---|
Slovak Academy of Sciences |
Slovakia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Genetic association | Association of selected single nucleotide polymorphisms with rheumatoid arthritis. | 1 day | No |
Secondary | Peripheral blood mononuclear cells reactivity | Reactivity and functional changes of peripheral blood mononuclear cells obtained from patients with rheumatoid arthritis in comparison to healthy controls. | 1 day | No |
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