Vascular Occlusion and Rheumatoid Arthritis

Rheumatoid Arthritis Clinical Trial

Official title:

Effects of Strength Training With Vascular Occlusion in Patients With Rheumatoid Arthritis: A Randomized Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01483157
• Other study ID #: vascular occlusion and RA
• Status: Recruiting
• Phase: N/A
• First received: November 29, 2011
• Last updated: February 27, 2014
• Start date: November 2011
• Est. completion date: November 2015

Study information

• Verified date: February 2014
• Source: University of Sao Paulo
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass resistance training alone. The investigators speculate this training strategy could be beneficial in patients with rheumatoid arthritis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: November 2015
• Est. primary completion date: November 2015
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 30 Years to 70 Years

Eligibility

Inclusion Criteria:

• female with rheumatoid arthritis

• Disease activity scores > 2.6

• use of anti-TNF-alpha drugs for at least 8 weeks

Exclusion Criteria:

• BMD < 20 kg/m2

• fibromyalgia

• cardiovascular disease

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Arthritis
• Arthritis, Rheumatoid
• Rheumatoid Arthritis

Intervention

Other:
• vascular occlusion with exercise trainig
twelve weeks of resistance training with vascular occlusion twice a week
• high intensity resistance training
twelve weeks of resistance training twice a week

Locations

Country	Name	City	State
Brazil	University of Sao Paulo - School of Medicine - Clinical Hospital	Sao Paulo

Sponsors (1)

Lead Sponsor	Collaborator
University of Sao Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	muscle strength		twelve weeks	No
Secondary	quality of life		twelve weeks	No