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The Effect of Certolizumab Pegol on MRI Synovitis and Bone Edema in Rheumatoid Arthritis Patients — PICS  

Rheumatoid Arthritis Clinical Trial

Official title:
The Effect of Certolizumab Pegol in Combination With Methotrexate on MRI Synovitis and Bone Edema and Patient Reported Outcomes as Measured Using an Automated Visit Manager System in Moderate to Severe Rheumatoid Arthritis Patients

Clinical Trial Summary

The purpose of this study is to determine whether Certolizumab pegol can rapidly reduce the inflammatory changes and inhibit erosions on hand and wrist MRI in patients with active moderate to severe rheumatoid arthritis.

Clinical Trial Description

The primary objective of this study is to evaluate the efficacy of CSP used in combination with MTX in patients with active moderate to severe RA by evaluating change from baseline in synovitis and bone edema MRI scores at week 6. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01213017
Study type Interventional
Source Oklahoma Medical Research Foundation
Contact
Status Completed
Phase Phase 3
Start date September 2010
Completion date April 2012
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