Rheumatoid Arthritis Clinical Trial
Official title:
A Multicenter, Open Label, Randomized, Parallel-group Study to Evaluate the Efficacy of Oral AB1010 in Adult Patients With Active Rheumatoid Arthritis With Inadequate Response to at Least One Disease Modifying Anti Rheumatic Drugs (DMARD)
The objective of this study is to evaluate the activity of 2 oral doses of AB1010 in subjects
suffering from active RA who have shown an inadequate response to one DMARD including MTX or
anti-TNF, after 3 months (12 weeks) of treatment.
The safety and efficacy will be evaluated on:
Rate of patients achieving ACR 20, 50, 70 and 90 DAS (disease activity score) after 3 months
treatment ACRn after 3 months treatment Therapeutic maintenance of AB1010 at 3 months Quality
of Life assessed by SF12 Health Assessment Questionnaire (HAQ) Clinical and biological safety
Pharmacokinetic profile of AB1010
n/a
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