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NCT05588817 Clinical Trial

Expression of IRAK1 Gene rs1059703-related Single- Nucleotide Polymorphisms in Egyptian Patient With Rheumatoid Arthritis

Rheumatoid Arthritis (RA) Clinical Trial

Official title:
Expression of IRAK1 Gene rs1059703-related Single- Nucleotide Polymorphisms in Egyptian Patient With Rheumatoid Arthritis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05588817
Other study ID # Soh_Med_22_10_15
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date December 30, 2022
Est. completion date December 1, 2023

Study information
Verified date October 2022
Source Sohag University
Contact Alaa A Abdel salam, Assistant lecturer
Phone 01099058889
Email alaa.eisa@med.sohag.edu.eg
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Rheumatoid arthritis (RA) is known as a long-lasting inflammatory autoimmune disease affecting the diarthrodial joints, which is diagnosed by inflammation and hyperplasia in synovium, generation of RF and anti-citrullinated protein antibody (ACPA), deformity of cartilage and bone, systemic injuries involving cardiovascular, pulmonary, psychological, and skeletal disorders (McInnes and Schett., 2011).

Recruitment information / eligibility
Status Recruiting
Enrollment 90
Est. completion date December 1, 2023
Est. primary completion date December 1, 2023
Accepts healthy volunteers No
Gender Female
Age group 17 Years to 85 Years
Eligibility Inclusion Criteria: - approval to sign an informed written consent, patient diagnosed rheumatoid arthritis, patient age range 17-85 year and both sexes are included. Exclusion Criteria: - Refusal to sign an informed written consent and patient with other autoimmune disease.

Study Design

Related Conditions & MeSH terms

Intervention

Genetic:
• PCR polymorphism
PCR polymorphism in Rhomatoid arthritis patients in Egypt

Locations
Country Name City State
Egypt Sohag university hospital Sohag

Sponsors (1)
Lead Sponsor Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary rs1059703 PCR polymorphism in rhomatoid arthritis patients PCR polymorphism 1 year
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