Optical Coherence Tomography Evaluation of Retinoschisis and Retinal Detachment

Retinoschisis Clinical Trial

Official title:

Use of Spectral Domain Optical Coherence Tomography to Differentiate and Follow-up Senile Retinoschisis and Retinal Detachment

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02682797
• Other study ID #: 19.08.2015
• Status: Completed
• Phase: N/A
• First received: February 5, 2016
• Last updated: August 5, 2016
• Start date: September 2013
• Est. completion date: July 2016

Study information

• Verified date: August 2016
• Source: Medical University of Vienna
• Contact: n/a
• Is FDA regulated: No
• Health authority: Austria: Ethikkommission
• Study type: Observational

Clinical Trial Summary

Retinoschisis is usually a rare self-limited disease and seldom shows progression. There a splitting of the neurosensory retina occurs usually in the inferior temporal. Patients usually have good visual acuity and are asymptomatic. Combination of an inner and outer layer hole is considered high risk factor for development of a schisis detachment. The most important differential diagnosis is an retinal detachment, since if misdiagnosed unnecessary treatment is provided. In clinical examination, both can appear very thin and transparent.

Therefore exact diagnosis of retinoschisis and retinal detachment has to be assessed and regular follow-up controls have to be conducted for sufficient recognition of progression.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 44
• Est. completion date: July 2016
• Est. primary completion date: July 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Male or female, at least 18 years of age.

• Ophthalmoscopic evidence of RS or RD

• Written informed consent has been obtained.

Exclusion Criteria:

• Progression of retinal detachment or retinoschisis requiring surgical treatment

• Contraindication to pupil dilation, known allergy.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Retinal Detachment
• Retinoschisis

Locations

Country	Name	City	State
Austria	Department of Ophthalmology, Medical University of Vienna, Austria	Vienna

Sponsors (1)

Lead Sponsor	Collaborator
Medical University of Vienna

Country where clinical trial is conducted

Austria, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Morphological findings in retinoschisis or retinal detachment in optical coherence tomography scans during follow-up		Baseline	No
Primary	Change or progression of disease measured in optical coherence tomography		2 years	No