Comparing Alternative Ranibizumab Dosages for Safety and Efficacy in Retinopathy of Prematurity — CARE-ROP

Retinopathy of Prematurity (ROP) Clinical Trial

Official title:
Multicenter Randomized Double Masked Parallel Design Exploratory Study to Assess Safety and Efficacy of Two Different Doses of Intravitreal Anti-VEGF Treatment With Ranibizumab (0.12 mg vs. 0.20 mg) in Infants With Retinopathy of Prematurity (ROP)

Status Completed

Clinical Trial Summary

This study is designed as an exploratory study to assess safety and efficacy of two different doses of the anti-VEGF agent ranibizumab (0.12 mg vs. 0.20 mg) in the treatment of infants with retinopathy of prematurity. Furthermore it shall help to improve safety in the treatment of ROP and provide explorative data on long-term effects of ranibizumab after intravitreal injection in neonates.

The primary objective is to assess clinical efficacy of ranibizumab in children with ROP

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02134457
Study type	Interventional
Source	University Hospital Freiburg
Contact
Status	Completed
Phase	Phase 2
Start date	August 2014
Completion date	January 2017

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See also
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