Retinoblastoma Clinical Trial
Official title:
Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated
Postoperative Treatment of Unilateral Retinoblastoma After Primary Enucleation according to histopathological risk factors of the International Retinoblastoma Staging Working Group.
Post operative chemotherapy +/- radiotherapy according to histopathological risk factors of the International Retinoblastoma Staging Working Group. - Low risk group : - No optic nerve involvement. - Intra and prelaminar involvement - No choroidal involvement. - Minimal superficial choroidal involvement . - Intermediate risk group, 2 sub groups : - Sub group 1 : - Retrolaminar involvement without Invasion of surgical margin associated or not to massive choroidal involvement - Anterior segment involvement. - Intrascleral involvement. - Sub Group 2 : - Isolated massive choroidal involvement. - High risk group : - Invasion of the surgical margin of the optic nerve - and/or microscopic extrascleral involvement - Optic nerve meningeal sheat involvement . ;
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