Retinoblastoma Clinical Trial
Official title:
Research on the Environment and Children's Health: Retinoblastoma
The purpose of the research study is to learn more about the causes of retinoblastoma and to identify possible risk factors in the parents of patients with retinoblastoma. This kind of study is called an epidemiology study and is often done by interviewing people with and without the disease. In the case of a childhood disease, the researchers ask about experiences of the parents and children before the disease developed.
Status | Completed |
Enrollment | 78 |
Est. completion date | June 2008 |
Est. primary completion date | June 2008 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Cases will be children with sporadic heritable RBL, i.e., bilateral RBL without a family history of the disorder. - Cases will be diagnosed with retinoblastoma in an approximately 7-year period, beginning January 1, 1998 and continuing until the sample size is reached. - The case family must reside in the continental U.S., Alaska, or Canada. - The case family must have a telephone in the household. - The patient's physician must give permission to contact the parents of the case. - The biologic father or mother of the case must be available and consent to be interviewed. - The father or mother must speak English or Spanish. - Genetic counseling regarding RB1 gene mutation analysis must be done prior to registration onto study. Exclusion Criteria: - Cases that do not meet the above criteria will be ineligible to participate and excluded from the study. |
Observational Model: Case Control, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Memorial Sloan-Kettering Cancer Center | New York | New York |
Lead Sponsor | Collaborator |
---|---|
Memorial Sloan Kettering Cancer Center | Milton S. Hershey Medical Center, New York Presbyterian Hospital, University of Pennsylvania |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | demographic and exposure information by telephone interview | 5 years 4 months | No |
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