Retinal Disease Clinical Trial
Official title:
Comparison Between Two Wide-field Imaging Systems on the Extent of Retinal Periphery Area Viewing
Fundus imaging has become an integral tool in retinal diagnosis. Although single-field fundus
photography covers a vital region of the retina, it leaves a large portion of the periphery
undiscovered.
Ultra-wide-field imaging systems allowed for visualization of peripheral perfusion
abnormalities in myopic eyes that were previously unknown.
In Austria, there are two different wide-field imaging systems available. The first device on
the market was the Optos (Optos PLC, Dunfermline, UK) and several years later the Clarus 500
(Carl Zeiss, Meditec AG, Jena, Germany) was introduced.
While both of the studied imaging systems have the possibility of a 200° view of the retina,
we would asses if the differences between the two devices affect the extent of retinal
periphery view and if ocular ametropies which come with different retinal pathologies would
affect the retinal periphery assessment.
Aim: To compare two CE-marked imaging systems concerning the extent of retinal periphery area
viewing.
We would like to perform a prospective observational study that would include patients
divided into three groups: myopic patients, hyperopic and emmetropic patients.
Fundus photography will be performed using two ultra-wide-field imaging systems (Optos,
Daytona, Optos PLC, Dunfermline, UK and Clarus, 500 Carl Zeiss, Meditec AG, Jena, Germany),
performed by the same investigator.
All images with sufficient quality will be exported and saved to hard-disk. The difference in
periphery view will be investigated as follows: two retinal photos for each patient will be
imported into Photoshop CS6 image-editing system (Adobe, version 13.0.0) where the anatomical
landmarks will be matched for each image and the borders will be compared to see if there are
differences in retinal periphery area viewing between the two devices.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04956237 -
Retinal Surgery With or Without Anesthesiologist, Comparison of Surgeon and Patient's Comfort
|
||
Recruiting |
NCT01432847 -
Cell Collection to Study Eye Diseases
|
||
Active, not recruiting |
NCT04130841 -
Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery
|
N/A | |
Recruiting |
NCT03713268 -
Intraoperative OCT Guidance of Intraocular Surgery II
|
||
Active, not recruiting |
NCT03872479 -
Single Ascending Dose Study in Participants With LCA10
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT04636307 -
Characterization of Retinal Disease Progression in Eyes With Non Proliferative Diabetic Retinopathy in Diabetes Type 2 Using Non-invasive Procedures (CHART)
|
||
Not yet recruiting |
NCT06451068 -
Peripheral Retina Robotically Aligned OCT Study
|
N/A | |
Recruiting |
NCT02921568 -
Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes
|
N/A | |
Completed |
NCT02315170 -
Assessment of Novel Intraocular Injection Guide
|
N/A | |
Completed |
NCT00069199 -
Optical Coherence Tomography Comparative Study
|
N/A | |
Withdrawn |
NCT03603990 -
Effect of Vitrectomy on the Evolution of Refractory Diabetic Macular Edema
|
N/A | |
Active, not recruiting |
NCT04123626 -
A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene
|
Phase 1/Phase 2 | |
Withdrawn |
NCT02445001 -
Erythrocyte Ghost Mediated Retinal Diagnosis
|
N/A | |
Completed |
NCT01468337 -
Topical Interferon Gamma-1b for Central Serous Chorioretinopathy
|
Phase 1/Phase 2 | |
Completed |
NCT01227993 -
Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
|
Phase 1/Phase 2 | |
Completed |
NCT00792259 -
Topcon 3D OCT-1000 Optical Coherence Tomography System
|
||
Completed |
NCT00035906 -
Research Study in Patients With Persistent Macular Edema
|
Phase 2 | |
Recruiting |
NCT05158699 -
Effectiveness of Periocular Drug Injection in CATaract Surgery
|
Phase 3 | |
Terminated |
NCT04110015 -
Assessment of Visual Function in Ophthalmic Disorders Using Virtual Visual Field Analysis
|
||
Recruiting |
NCT03592017 -
Performance of Long-wavelength Autofluorescence Imaging
|
N/A |