Respiratory Tract Infections Clinical Trial
Official title:
The Efficacy of Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic Trial
The use of both levamisole & Isoprinosine has both synergistic and complementary effect in the treatment of COVID 19 infection
Study design: Randomized controlled trial, randomization by closed envelope technique
Informed consent will be written for each patient of either group
At the beginning of the study all patients will have the following investigations done: CBC
with differential, ESR, PCR for COVID 19, D dimer and CT chest and confirmed cases will
included in the study
Pregnant and lactating women together with children with other comorbidities will be excluded
from the study
Study groups:
Duration of the study is 4 weeks
Both groups with persistent COVID 19 symptoms that require hospitalization
Group 1: 30 patients with confirmed COVID19 infection and sharing clinical features like
fever, malaise, sore throat, runny nose, persistent cough &dyspnea, requiring hospitalization
Group 2: control group: 30 patients
Treatment endpoint • Cure of patients: Improvement of symptoms Laboratory findings ESR and
total leucocytic count returning to normal PCR negative Radiological improvement
• Worsening of symptoms or fatalities
;
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