Respiratory System Abnormalities Clinical Trial
Official title:
Comparison of Breathing Pattern During PSV and NAVA
Comparison of Breathing pattern during mechanical ventilation. Two modes of mechanical ventilation are compared (Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist)
Eligibility : healthy subject without respiratory complications in the past
Subjects will breath spontaneously without mechanical ventilation, with Pressure Support
Ventilation and with Neurally Adjusted Ventilatory Assist during.
Three levels of pressurisation will be tested : 5 cmH2O, 8 cmH2O and 12 cmH2O Duration of
each condition will be about 15 minutes.
Measurements will include:Flow, airway pressure, SaO2, PtCO2, diaphragmatic
electromyography, chest wall motion by optoelectronic plethysmography
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science
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