Respiratory Disorders Clinical Trial
Official title:
An Observer-blind Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals' Non-typeable Haemophilus Influenzae (NTHi) Investigational Vaccine (GSK2838497A) in Current and Former Smokers
The purpose of this study is to assess the safety, reactogenicity and immunogenicity of 8 different formulations of investigational NTHI vaccine in current and former smokers, 50-70 years of age.
This Protocol Posting has been updated following Protocol Amendment 1, dated 10 October 2012, leading to a change in an inclusion criterion. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01443845 -
Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)
|
Phase 4 | |
| Withdrawn |
NCT00844935 -
Electrocardiographic Autonomic Function Measures in Mechanically Ventilated Patients
|
N/A | |
| Completed |
NCT01395849 -
Drug Use Investigation for ADOAIR (Fluticasone/Salmeterol)
|
N/A | |
| Completed |
NCT03557645 -
Ventilator Hyperinflation and Hemodynamics
|
N/A | |
| Completed |
NCT03281876 -
A Study to Test if the Vaccine is Working Well in Chronic Obstructive Pulmonary Disease (COPD) Patients Aged 40 to 80 Years Old to Reduce Episodes of Worsening Symptoms and to Gather Further Information on Safety and Immune Response.
|
Phase 2 | |
| Completed |
NCT01395862 -
Special Drug Use Investigation for ADOAIR (Fluticasone/Salmeterol)
|
N/A | |
| Completed |
NCT01476046 -
Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects.
|
Phase 1 | |
| Completed |
NCT01587807 -
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Inhaled GSK1995057
|
Phase 1 | |
| Completed |
NCT00835003 -
Timing of Planned Caesarean Section and Morbidity of the Newborn
|
N/A | |
| Completed |
NCT03443427 -
A Study to Test if a Third Dose of the Vaccine is Safe in Current and Former Smokers Aged 40 to 80 Years Old and to Gather Information on the Immune Response Following the Third Dose of the Vaccine
|
Phase 2 | |
| Completed |
NCT01360398 -
Infectious Pathogens in Acute Respiratory Illness in Adults and Elderly
|
N/A | |
| Completed |
NCT03201211 -
A Long Term Follow-up Study up to 4 Years After Study Vaccination to Assess Immunogenicity and Safety of the Investigational Vaccine in Adults
|
Phase 1 | |
| Completed |
NCT02075541 -
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.
|
Phase 2 | |
| Completed |
NCT00455767 -
Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients
|
Phase 2 | |
| Withdrawn |
NCT01505556 -
Proprioceptive Postural Control and Diaphragm Paresis
|
||
| Completed |
NCT01505582 -
Inspiratory Muscle Training and Low Back Pain
|
N/A | |
| Completed |
NCT02322671 -
Relative Bioavailability Study of Two Montelukast Sodium (GW483100) 5 Milligrams (mg) Chewable Tablets and One Reference Montelukast Sodium 5 mg Chewable Tablet in Healthy Adult Subjects
|
Phase 1 | |
| Completed |
NCT01818024 -
A Study to Investigate the Safety Tolerability Pharmacokinetics, and Pharmacodynamics of Inhaled and Intravenous GSK2862277 in Healthy Volunteers
|
Phase 1 | |
| Recruiting |
NCT02316379 -
Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration
|
Phase 1/Phase 2 | |
| Completed |
NCT01516437 -
A Study to Assess Immunity to Specific Microbial Antigens in Healthy Smokers and Non-smokers and in Subjects With Stable COPD
|
N/A |