Resistance Training Clinical Trial
Official title:
The Role of Resistance Training in Non Alcoholic Fatty Liver Disease
The aim of the study is to evaluate the effect of RT on clinical and metabolic parameters in patients with NAFLD.
Background: Non Alcoholic Fatty Liver Disease (NAFLD) is the most prevalent liver disease in
developed countries with a prevalence rate of 20-30 % of adults. About 10-25% of these
individuals are estimated to meet the current diagnostic criteria for Non Alcoholic
Steatohepatitis (NASH) and some may progress to Cirrhosis and liver failure. NAFLD is now
recognized as the hepatic manifestation of the metabolic syndrome. Recent data shows that
NAFLD might also predict the tendency to develop diabetes mellitus and coronary artery
disease. The drug of choice for NAFLD is yet to be found. The recommended treatment of NAFLD
includes weight reduction and Physical Activity (PA), but the data of the effect of
Resistance Training (RT) PA on NAFLD is scant.
Aim of the study: To evaluate the effect of RT on clinical and metabolic parameters in
patients with NAFLD. Study design: Randomized Clinical Trial. Patients will be randomly
allocated to 2 arms (intervention and control). The intervention arm will perform RT,
whereas control arm will be advised to perform home stretching. Medical examination will be
performed at week 0 (baseline) and at week 13 using uniform protocols.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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