Residual Neuromuscular Blockade Clinical Trial
Official title:
Incidence and Severity of Residual Neuromuscular Blockade With Application of a Protocol for Paralysis and Neostigmine Reversal of Rocuronium
NCT number | NCT02660398 |
Other study ID # | 50608 |
Secondary ID | |
Status | Completed |
Phase | Phase 4 |
First received | |
Last updated | |
Start date | January 2016 |
Est. completion date | January 2017 |
Verified date | May 2019 |
Source | University of Washington |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This prospective study will take place at Harborview Medical Center (HMC) and the University of Washington Medical Center (UWMC), and will enroll adult patients undergoing abdominal surgery. The purpose of this study is to identify if the use of a specific plan to managing muscle relaxants will help decrease the risk of muscle weakness after general anesthesia with muscle relaxation in a population of patients undergoing abdominal surgery.
Status | Completed |
Enrollment | 78 |
Est. completion date | January 2017 |
Est. primary completion date | January 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Adults age 18 or older - Will undergo open or laparoscopic abdominal surgery expected to last <6 hours at HMC or UWMC - Have ASA physical status I-III - Scheduled to have general anesthesia with at least 1 dose of nondepolarizing NMBD for endotracheal intubation or maintenance of neuromuscular block (NMB) Exclusion Criteria: - Allergy to NMBDs - Patients with neuromuscular disease (myasthenia gravis or muscular dystrophy) - Pregnant or lactating women - Non-English speaking - Unable to provide informed consent |
Country | Name | City | State |
---|---|---|---|
United States | University of Washington Medical Center | Seattle | Washington |
Lead Sponsor | Collaborator |
---|---|
University of Washington |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Incidence of residual paralysis | The incidence of residual paralysis defined as a TOF ratio <0.9 will be measured. | The outcome measure will be assessed at time of extubation | |
Secondary | Incidence of severe residual paralysis | The incidence of severe residual paralysis defined as a TOF ratio <0.7 will be measured. | The outcome measure will be assessed at time of extubation |
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