Residual Neuromuscular Blockade Clinical Trial
Official title:
Predictor of Residual Neuromuscular Blockade in Recovery Room After General Anesthesia
Background When general anesthesia was performed, neuromuscular blocking agents (NMBAs) are
frequently used for facilitate tracheal intubation and keep patient still and relax during
surgery. Unfortunately, residual neuromuscular blockade are important complication.
There are many factors that affect neuromuscular blockade and may prolong effect of NMBAs
which we already know about that such as body temperature, drugs, some kind of diseases.
However there are no recent studies that mention about other factors. The purpose of this
study is to find out other factors that affect NMBAs effect to improve patient safety.
Methods The study is a prospective, non-randomized, blinded, observational study.
222 patients will be included in this study and will be performed general anesthesia.
Anesthetic technique and agent which are used depend on regular staff. Information of patient
will be collected are age, sex, weight, height, ASA classification, anesthetic technique,
anesthetic and surgical time, amount of inhalation agent, amount of NMBAs, amount of opioids
and reversal agents.
After anesthesia finish, patient will be brought to recovery room and Train Of Four watch®
will be placed and record Train Of Four ratio by this research staff. Train Of Four ratio <
0.9 will be defined as there is residual neuromuscular blockade in this patient.
All patients will be divided into 2 groups: residual blockade group(patient who have train of
four <0.9 after surgery) and no residual blockade group(patient who have train of four >0.9).
All factor of each group will be compared between. Statistical will be analyzed to find
significant factor which affect neuromuscular blockade.
study about residual neuromuscular blockade ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT04619225 -
Cardiac Output and Recovery Time
|
N/A | |
| Recruiting |
NCT05992090 -
Neuromuscular Blockade Monitoring Using Kine-myography vs Electromyography.
|
||
| Completed |
NCT03585400 -
Validation of the REPS Prediction Tool
|
||
| Terminated |
NCT01678625 -
Electromyographic Assessment of Onset and Recovery of Neuromuscular Blockade
|
||
| Completed |
NCT03417804 -
Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
|
||
| Completed |
NCT03111082 -
Incidence of Postoperative Neuromuscular Blockade in Post-Anesthesia Care Unit at Parkland Hospital: Does Size Matter?
|
||
| Completed |
NCT04244266 -
Observational Study in Bariatric Surgery
|
||
| Completed |
NCT02939911 -
Residual Neuromuscular Blockade in Pediatric Anesthesia
|
||
| Completed |
NCT02660398 -
Incidence and Severity of Residual Neuromuscular Blockade
|
Phase 4 | |
| Completed |
NCT03920670 -
Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
|
N/A | |
| Completed |
NCT01837498 -
Reversal of Neuromuscular Blockade in Thoracic Surgical Patients
|
||
| Completed |
NCT02213848 -
Effect of Calcium Chloride on Recovery From Neuromuscular Blockade
|
N/A | |
| Completed |
NCT04352127 -
Visual and Electromyography Assessments in Response to Train-of-Four Stimulation of the Ulnar Nerve
|
N/A | |
| Completed |
NCT04312256 -
Thumb vs Great Toe Recovery
|
N/A | |
| Completed |
NCT04352140 -
Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting
|
N/A | |
| Withdrawn |
NCT03574337 -
Residual Neuromuscular Blockade in Cardiac Surgery Patients
|
Phase 4 |