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A Study of TCD601 in de Novo Renal Transplant Recipients — ASCEND  

Renal Transplantation Clinical Trial

Official title:
A 12-Month, Randomized, Open-Label, Phase IIA Study Evaluating the Safety and Efficacy of Siplizumab in Combination With Belatacept and MPA Compared to Standard of Care Immunosuppression in de Novo Renal Transplant Recipients (ASCEND)

Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of TCD601 in combination with Belatacept when compared to standard of care immunosuppression therapy in de novo renal transplant patients.

Clinical Trial Description

The purpose of this study is to evaluate the safety and efficacy of TCD601 (siplizumab), an anti-CD2 monoclonal antibody, in combination with a CNI-free regimen of belatacept, MPA, and corticosteroids compared to a standard of care CNI-based regimen of tacrolimus, ATG, MPA and corticosteroids in de novo renal transplant patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05669001
Study type Interventional
Source ITB-Med LLC
Contact Britain Javens, MS
Phone (212) 969-7823
Email britain.javens@itb-med.com
Status Recruiting
Phase Phase 2
Start date December 28, 2023
Completion date October 2026
View Details
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