Renal Transplant Surgery Clinical Trial
Official title:
Can Goal Directed Hemodynamic Management Improve Renal Outcome After Renal Transplant Surgery?
This study is designed to compare the incidence of delayed graft function in patients following renal transplant surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.
Volume assessment and management during renal transplantation is one of the most challenging
problems the anesthetist has to deal with. It seems sensible that individualized volume
management and hydration therapy during the operation and during the stay at the intensive
care unit could improve perfusion of the transplanted organ resulting in a better transplant
function. Aim of this study is to investigate the impact of a goal directed hemodynamic
management on incidence of delayed graft function (DGF) after renal transplant surgery.
Therefore patients will be randomized in one of two groups, the PiCCO group with goal
directed hemodynamic management during operation and during the ICU-stay and the control
group with hemodynamic management performed according to heart rate, blood pressure and
central venous pressure.
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