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Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal Impairment

Renal Insufficiency Clinical Trial

Official title:
AN OPEN-LABEL, PARALLEL-GROUP, PHARMACOKINETIC STUDY OF MULTIPLE INTRAVENOUS DOSES OF AZTREONAM AND AVIBACTAM IN SUBJECTS WITH SEVERE RENAL IMPAIRMENT AND NORMAL RENAL FUNCTION

Clinical Trial Summary

This Phase 1 study is being conducted to evaluate the effect of severe renal impairment on the PK, safety and tolerability of Aztreonam-Avibactam. Results from this study along with previous renal impairment data from each of the Aztreonam-Avibactam components will be used to confirm the proposed dosing adjustment in severe renal impairment which was based on modelling/simulation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04486625
Study type Interventional
Source Pfizer
Contact
Status Completed
Phase Phase 1
Start date August 10, 2020
Completion date October 18, 2021
View Details
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