Renal Insufficiency, Chronic Clinical Trial
Official title:
Effects of the Supplementation With Omega 3 Fatty Acids in Patients With Chronic Renal Disease
To study the tolerance and efficacy of an omega 3 fatty acids supplement on renal and vascular function and inflammatory parameters in patients with chronic renal disease
In a double blind trial in patients with chronic renal disease, the effects of a 3.7 g
supplement of docosahexanoic and eicosapentanoic acids or a supplement of a similar dose of
corn oil during 12 weeks, will be assessed on the following parameters:
1. Urine albumin excretion
2. Renal function measured with serum creatinine, cystatin C and beta-2 microglobulin
3. Carotid intima media thickness and pulse wave velocity
4. Inflammation status assessed measuring serum levels of C reactive protein and
interleukin 6
5. Metabolic control of diabetes
6. Serum lipid levels
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