Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients

Status Completed

Clinical Trial Summary

Will use a subset of the main study cohort of transgender or non-binary individuals to evaluate the relationships between self-reported exogenous hormone use, endogenous hormone values, renal biomarkers, drug levels and directly measured renal function.

Clinical Trial Description

This cross-sectional sub-study will use a subset of the main study cohort of transgender (TG) or non-binary (NB) individuals to evaluate the relationships between self-reported exogenous hormone use, endogenous hormone values (serum estradiol, estrone, free/total testosterone), renal biomarkers, drug levels (measured by tenofovir diphosphate, TFV-DP, and emtricitabine triphosphate, FTC-TP, on dried blood spot cards and urine) and directly measured renal function (iohexol clearance). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04742816
Study type	Interventional
Source	University of California, San Diego
Contact
Status	Completed
Phase	Phase 4
Start date	September 17, 2020
Completion date	December 31, 2021

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