Immunotherapy of Chronic Kidney Failure

Status Not yet recruiting

Clinical Trial Summary

Kidney failure can result from inflammatory renal disease in the context of autoimmunity because the kidney is targeted by host's immune response against self. There are many causes to this, but abnormal kidney function tests, i.e., BUN and creatinine, can reveal the disease. Oral delivery of kidney cells is ought to produce the immune tolerance - phenomenon is known as oral tolerance. Preliminary studies produced convincing evidence that this hypothesis holds true and has not produced any adverse side effects. Intended open label Phase II aims to confirm these findings.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04377243
Study type	Interventional
Source	Immunitor LLC
Contact	Aldar Bourinbaiar, MD/PhD
Phone	13014760930
Email	aldar@immunitor.com
Status	Not yet recruiting
Phase	Phase 2
Start date	June 16, 2020
Completion date	September 1, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03246984` - VALUE- Vascular Access Laminate eUropean Experience. A Post Market Surveillance Study to Assess the Safety and Effectiveness of VasQ	N/A
Completed	`NCT05787080` - Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS)	N/A
Completed	`NCT05585268` - Electronic Decision Support for Deprescribing in Patients on Hemodialysis	N/A
Completed	`NCT02332811` - An Open Label, Dose Titration Study of Sevelamer Carbonate Tablets & Powder in Hyperphosphatemic CKD Patients	Phase 3
Withdrawn	`NCT03093740` - Direct-acting Antiviral Therapy to Prevent HCV Infection for HCV Positive Donor to HCV Negative Recipient Kidney Transplant	Phase 4
Recruiting	`NCT04908345` - Methadone Anesthesia For Kidney Transplant Receptors	Phase 3
Completed	`NCT05769686` - Laparoscopic Donor Nephrectomy Score, a New Scoring System for Preoperative Prediction of Difficulty of Laparoscopic Donor Nephrectomy
Completed	`NCT03949036` - Comparison of Two Different Preload Targets of Stroke Volume Variation During Kidney Transplantation	N/A
Completed	`NCT04204005` - Probiotics and Low Protein Diet in Advanced Chronic Kidney Disease	N/A
Completed	`NCT03658876` - Predictors of Response to Iron and Erythropoietin Stimulating Agents	Phase 4
Active, not recruiting	`NCT05418816` - SelfWrap-Assisted Arteriovenous Fistulas	N/A
Completed	`NCT06454981` - Clinical Trial for Effectiveness and Safety Evaluation of Hemodiafilter	N/A
Active, not recruiting	`NCT03436368` - Continuous Spinal Anesthesia in Renal Transplantation	N/A
Recruiting	`NCT03778944` - Enhancing Renal Graft Function During Donor Anesthesia	N/A
Recruiting	`NCT05077163` - Patients With Acute Renal Failure During Severe COVID-19
Recruiting	`NCT05521425` - Randomized Controlled Trial on 3D Printed Assistive Device for Continuous Ambulatory Peritoneal Dialysis	N/A
Active, not recruiting	`NCT05381961` - Observational Study of BIS in Hemodialysis Patients
Completed	`NCT03781726` - Multi-center Study to Transplant Hepatitis-C Infected Kidneys	Phase 4